Forever Chemical PFOS Linked to Gum Disease by Genetic and Multiomics Evidence
An integrated study combining global burden data, Mendelian randomization, multiomics, structural simulation, and cell experiments links PFOS exposure to increased ...
Tag: molecular docking
Plant Compounds Emerge as Multitarget Leads Against Alzheimer’s Disease in Virtual Screen
A computational screen of 2,847 plant compounds against ten Alzheimer's-related proteins identified 36 multitarget phytochemicals with stable binding and literature-backed ...
Scientists Switch Off a Key Mechanosensor in Tendon Cells and Map What Breaks
A conditional knockout study shows that deleting the mechanosensor YAP in stretched tendon cells disrupts a broad lipid-metabolism and immune-linked ...
Machine Learning Uncovers Six Oxidative Stress Genes That Could Catch Sepsis in Children Early
A machine learning and gene network study has identified six oxidative stress-related genes with near-perfect diagnostic accuracy for pediatric sepsis ...
Scientists Build Screening Toolkit to Find Bait Ligands for Antibacterial Protein Degradation Drugs
Researchers have developed fluorescence polarization and thermal shift screening methods to identify small-molecule bait ligands for the bacterial ClpC N-terminal ...
Indanone Compounds Show Promise Against Parkinson’s and Alzheimer’s in Animal Studies
Indian researchers have synthesized arylidene indanone derivatives that restore motor function in Parkinson's model mice and memory in Alzheimer's model ...
Fermented Banana Waste Turned Into Biodegradable Beads That Lure Fruit Flies
Researchers converted fermented banana and other fruit waste into biodegradable sodium alginate beads that attracted vinegar flies at nearly 83 ...
Papaya Leaf Flavonoids Show Multi-Target Chemopreventive Effects Against Breast Cancer in Rats
New research shows that aqueous and flavonoid-rich extracts of Carica papaya leaves suppress DMBA-induced breast cancer in rats by restoring ...
Buckwheat Compound Fagopyrine Emerges as Computational Lead for AKT1 Cancer Drug Design
A pan-cancer computational study identified the buckwheat-derived compound fagopyrine as a strong predicted binder to the AKT1 kinase, positioning it ...
Benzothiazole Emerges as a Promising Weapon Against Drug-Resistant Malaria
A new review argues that benzothiazole derivatives, acting through DHFR inhibition and heme detoxification, could yield next-generation antimalarials effective against ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!