Embryonic Cells Squeeze Through Tight Tissues Without Breaking Their DNA
Zebrafish neural crest cells migrating through extremely confined embryonic tissues deform their nuclei dramatically yet avoid nuclear envelope rupture and...
Bile Acid Sensor FXR Drives Liver Regeneration by Rebuilding Its Immune Cell Army
New research shows that the bile acid receptor FXR coordinates monocyte recruitment and Kupffer cell proliferation through CCR2 and CSF1/PI3K/Akt...
Cellular Stress Switch IRE1α Emerges as Next-Generation Target for Type 2 Diabetes
A new review argues that the evolutionarily conserved IRE1α/XBP1 stress-signaling pathway, which governs protein folding, inflammation and insulin action, offers...
Chromosome Crowding Sets the Size of the Mitotic Spindle Across Life
A cross-species study shows that the width of the mitotic spindle scales with the cube root of genome size because...
New Turkish Sheep Breed Hits the Sweet Spot: 40 Kilograms for Perfect Lamb Meat
The first comprehensive study of Türkiye's Lalahan sheep shows the new crossbred genotype delivers efficient growth and lean carcasses, with...
Chemical Tag on mRNA Reveals Hidden Switch That Controls Hair Growth Cycles
A new PLOS Genetics study shows that the RNA modification enzyme METTL1 controls hair follicle cycling by stabilizing HOXC13 messenger...
Cellular Recycling Routes Reshape How Hormone Receptors Send Their Signals
A new computational model shows that a small pool of internalized follicle-stimulating hormone receptors can drive outsized endosomal signaling, revealing...
Scientists Uncover Molecular Off Switch That Controls Nitrogen Fixation in Microbes
Researchers using cryo-electron microscopy have discovered that methanogen nitrogenase forms an inactive protein supercomplex that acts as a molecular off...
Cell Death Gets a Map: How mTORC2 Positions Mitochondria to Punch Holes in the Cell Membrane
Cell death is rarely a tidy affair, but a newly proposed framework argues that one recently identified form of lytic...
Empty Fruits Are Quietly Sabotaging Plant Germination Science, Rosemary Study Warns
A new rosemary study shows that unnoticed seedless fruits can reverse or erase the apparent effects of temperature, water and...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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