Ancient Chinese Herbal Formula Decoded: How Danggui Buxue Decoction Fights Chronic Kidney Disease
A new study combines UPLC-MS/MS, network pharmacology, and animal experiments to show how the 800-year-old Chinese formula Danggui Buxue Decoction ...
Tag: molecular docking
FDA-Approved Antibiotics Show Promise Against Wnt-Driven Colorectal Cancer
Researchers used virtual drug repurposing to identify FDA-approved antibiotics Carbenicillin and Ceforanide as inhibitors of the β-catenin/Tcf4 interaction, showing anti-proliferative ...
A Traditional Medicinal Root Reveals Antioxidant and Anti-Inflammatory Potential in New Study
An integrated study of Liriope platyphylla root identifies 63 lipophilic compounds and shows antioxidant and anti-inflammatory effects in macrophage cells.
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing Precise
A new review outlines how aptamer-guided nanocarriers could finally deliver CRISPR-Cas9 gene editing specifically to tumor cells, integrating molecular targeting, ...
Graphene-Infused Coatings May Help Dental Implants Bond Better to Bone
A new computational study shows that adding graphene oxide to hydroxyapatite coatings substantially strengthens predicted binding to bone-building proteins and ...
Tree Gum Compounds Show Potent Anti-Cancer Power Against Lung Cancer Cells
Bioactive compounds from the medicinal tree Pistacia integerrima suppress the growth and migration of lung cancer cells by targeting PI3K, ...
Worm Drug Praziquantel May Fight Liver Fibrosis by Targeting Estrogen Receptor ESR1
A network-based study finds that the antiparasitic drug praziquantel alleviates liver fibrosis by targeting the estrogen receptor gene ESR1 in ...
Soy Compound Genistein Shows Promise Against Diabetes-Linked Bone Loss
An integrated computational and animal study shows that the soy isoflavone genistein targets five key genes to simultaneously lower blood ...
Scientists Design a Computationally Engineered mRNA Vaccine Candidate Against Sleeping Sickness Parasite
Researchers have used immunoinformatics and reverse vaccinology to design a multi-epitope mRNA vaccine candidate against Trypanosoma brucei, the parasite that ...
Scientists Validate a Bacterial Lipase Model That Could Speed Up Anti-Obesity Drug Discovery
Indonesian researchers have validated the thermostable bacterial enzyme lipase ITB 2.1 as a reliable structural and functional model for screening ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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