A matched-cohort study finds that Parkinson's patients with nocturnal hypokinesia show slower turning, poorer backward walking, and fewer daily steps,...

Researchers used a consumer tablet app to capture facial blendshape features that objectively quantify Parkinson's hypomimia, revealing asymmetry and interaction...

A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a...

New research in human neurons shows that the ALS-linked RNA-binding protein TDP-43 is transported along axons by a flexible fleet...

Researchers combined mass spectrometry, machine learning and animal experiments to reveal how the traditional Chinese formula Bushen-Yizhi protects against Alzheimer's-like...

New research shows that astrocytes carrying the C9ORF72 mutation disrupt mitochondrial transport in motor neurons through a contact-dependent bioenergetic mechanism...

A new study finds that about fourteen percent of Parkinson's patients without recognised pathogenic mutations show LRRK2 pathway activation as...

A new letter in the Journal of Clinical Sleep Medicine argues that sleep changes in Parkinson's disease should be read...

A validated PacBio HiFi long-read sequencing workflow detects low-frequency mitochondrial DNA heteroplasmy with near-perfect accuracy and reveals dynamic variant trajectories...

A two-year Czech study used biweekly smartphone tasks to detect subtle motor progression in people with isolated REM sleep behavior...