One in Three Parkinson’s Patients Faces Cognitive Decline, Landmark Analysis Finds
A meta-analysis of over 103,000 Parkinson's disease patients finds cognitive impairment affects roughly one in three, with orthostatic hypotension, diabetes,...
Deaths Involving Both Alzheimer’s and Cancer Decline Slightly Yet Grow in Number Among Older Americans
A 25-year national analysis finds that age-adjusted U.S. death rates involving both Alzheimer's disease and cancer among adults aged 65...
How one assay turned prion detection into a revolution across neurodegeneration
A new review in Acta Neuropathologica chronicles how Byron Caughey's development of the RT-QuIC assay revolutionized prion detection and seeded...
Early Weight Loss in ALS Signals Faster Decline, but Standard Energy Formulas Fall Short
A prospective Australian study shows that early weight loss in amyotrophic lateral sclerosis marks a subgroup with faster decline and...
Common Antidepressants Disrupt the Sleep Paralysis That Keeps Dreamers Still
A large Cleveland Clinic study of 1,474 sleep studies found that SSRIs and SNRIs, but not tricyclic antidepressants, are associated...
Parkinson’s Doubles Hip Fracture Risk, Yet Osteoporosis Drugs Are No More Likely After Breaks
A nationwide Finnish cohort study found that people with Parkinson's disease receive anti-osteoporosis medications at rates similar to or higher...
Chemical Tags on Blood Proteins Reveal a New Window Into Alzheimer’s Disease
Researchers at the University of Tokyo have produced the first map of lysine acetylation marks across plasma proteins in Alzheimer's...
Palm Oil and Myristic Acid Nanoparticles Could Smooth Out Parkinson’s Drug Delivery
Researchers engineered a lipid nano-emulsion from solid myristic acid and liquid palm oil that encapsulates L-DOPA in sub-100-nanometer particles and...
Spinal Fluid Inflammatory Proteins Reveal Why ALS Progresses at Different Speeds
Researchers profiling inflammatory proteins in cerebrospinal fluid have identified a signature, including SIRT2 and MMP-1, that distinguishes slow from fast...
Molecular Chaperones Keep ALS Protein Droplets From Hardening Into Disease
A new review in BMC Medicine argues that ALS arises when the cellular systems that keep reversible protein condensates from...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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