Weight Loss Rewires Cholesterol Metabolism, but Tiny RNAs Are Not the Driver
A Dutch randomized trial finds that diet-induced weight loss shifts cholesterol metabolism in abdominally obese men from a synthesizing to ...
Tag: Biomarkers
Two Proteins Found on Nearly All Liver Cancer Cells Point to a Dual-Target CAR-T Strategy
A study of 140 liver tumor samples shows that Glypican-3 and AXL are co-expressed in nearly all hepatocellular carcinomas, supporting ...
qBiCo: New Quality-Control Test Exposes Hidden Flaws in DNA Methylation’s Gold-Standard Method
A new five-plex qPCR assay called qBiCo provides the first comprehensive quality control for bisulfite-converted DNA, revealing that commercial conversion ...
When Gut Microbes Turn Bad: Dysbiosis Emerges as a Driver and Detector of Digestive Cancers
A new review details how disruptions in the gastrointestinal microbiome drive cancer through inflammation, genotoxins, and immune evasion, while microbial ...
Hidden Bacteria Inside Stomach Tumors May Signal How Aggressive Gastric Cancer Will Be
A dual-sequencing study of gastric tumors reveals a distinctive bacterial signature linked to cancer stage and biomarker levels.
Gene Networks Point to Interferon Decline as Driver of Severe Dengue in India
A whole-blood transcriptomic study of 112 dengue patients in New Delhi links depressed interferon responses and altered glycosylation pathways to ...
Two Molecular Heart Failure Types Revealed by Deep Protein Maps of the Failing Heart
Proteomic and phosphoproteomic profiling of 149 failing human hearts reveals two molecular subgroups of heart failure that cut across clinical ...
Metabolite Fingerprint in Seminal Plasma Could Explain Hidden Male Infertility
A systematic review of twenty metabolomic studies has identified consistently deregulated metabolites in the seminal plasma of infertile men, pointing ...
Tiny Vesicles Between Muscle and Bone May Unlock New Treatments for Osteosarcopenia
A new review in the Journal of Translational Medicine details how exosomes mediate communication between muscle and bone and evaluates ...
Chemical Tags on RNA Drive Cancer Spread and Treatment Failure, Review Finds
A comprehensive review in Molecular Cancer details how chemical modifications to RNA molecules regulate tumor metastasis and therapy resistance, opening ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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