Biology
Japanese Colorectal Cancer Reveals Prevalence, Timing, and Microbiome Signatures of Colibactin Mutations
Colorectal cancer is often described as a disease written into the genome, but the authors of a new study argue...
New CAF Population Directs Highly Suppressive Regulatory T Cells in Lung Tumors
A previously unrecognized population of cancer-associated fibroblasts appears to act as a spatial organizer for immune suppression in lung cancer,...
Protein nanocrates overcome air–water interface artifacts in cryo-EM
Cryo-electron microscopy has transformed structural biology by allowing scientists to visualize proteins and other biological machines at near-atomic resolution. Yet...
Nucleosomes and IDRs Restrain GCN4’s Promiscuous Binding on Minichromosomes
A new study is reshaping the way scientists understand how transcription factors find their targets inside the crowded genome. Researchers...
Photoprotection, carbon reallocation drive Dendropanax trifidus drought recovery in future climates
A subtropical tree has revealed how forests may survive a future defined by hotter temperatures, rising atmospheric carbon dioxide and...
Framework combines multiple evidence streams to discover biomarkers in small-sample time-series transcriptomics
Small-sample RNA-sequencing studies often promise a window into the molecular changes that accompany disease, treatment response, or infection. Yet when...
Rainfall Shapes Rhizosphere Microbial Communities Across Two Alpine Wetland Types
Rainfall is doing more than replenishing water in alpine wetlands: it may be steering the microscopic communities that live around...
Hunter-gatherers sleep as long as modern humans, but at different times
The idea that every adult needs exactly eight hours of sleep has become one of modern wellness culture’s most durable...
Study reveals how PRC2 guides preimplantation development and primordial germ cell fate
A new study has revealed that the epigenetic regulator PRC2 performs different, stage-specific jobs during the earliest phases of mammalian...
Tropical Forest Regeneration Costs and Ecological Benefits Vary Widely
Tropical forests may be able to return naturally across millions of square kilometres of degraded land, offering a powerful but...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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