A study of Fragile X syndrome model mice finds that microglia and astroglia over-engulf synaptic material and that glial signaling...

A benchmarked computational framework called BayesPrism-DWLS infers cell-type proportions and cell-type-specific gene expression from bulk RNA-seq and spatial transcriptomics data...

A new method called CSDE uses a small set of expert-validated cells to correct systematic preprocessing errors in spatial transcriptomics...

An integrated analysis of human carotid plaque transcriptomes and macrophage experiments suggests that elevated BCAP31 in atherosclerotic lesions may reflect...

A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and platform choices substantially...

A computational framework linked spatial gene-expression gradients to net-production direction under steady-state and positive-flow assumptions, with reproducible directions in human...

An exploratory whole-blood analysis identified a shared B-cell-associated gene signature in women with hypothyroidism and subclinical atherosclerosis, but small samples...

A new review argues that innate lymphoid cells act as central coordinators of barrier tissue homeostasis, and that their dysregulation...

A transcriptomics-guided study reveals how CO2 availability shapes acetate and ethanol production in the acetogenic bacterium Clostridium aceticum, identifying serine...

A new letter to the editor challenges a transcriptomic study linking collagen-rich extracellular matrix to postoperative angiogenesis in Moyamoya disease,...