Biology
BioSIFTR infers gut microbiome functions from shallow sequencing
BioSIFTR inferred microbial functions from shallow shotgun sequencing using biome-specific genome catalogues and outperformed similar approaches in synthetic-community and gut-microbiome...
PRKAR2A Emerges as Candidate Spatial cAMP–PKA Router in TNBC
A critical review finds that PRKAR2A is a plausible spatial regulator of cAMP–PKA signalling in triple-negative breast cancer, although current...
Molecular survey finds widespread Cryptosporidium and limited Giardia in Victorian pigs
A survey of 626 pig faecal samples from 37 Victorian farms found Cryptosporidium in 51.1% of samples and Giardia duodenalis...
Gene architecture predicts isoform diversity across four genomes
Longer introns, shorter exons and more complex gene organization were consistently associated with higher transcript-isoform diversity in humans, mice, flies...
Efficacy of statistical and design interventions for improving reproducibility in biomedical research
A registered-report simulation study found that statistical and design interventions for improving biomedical research reproducibility had mixed and measure-dependent effects.
Alpine moth study separates two species using anatomy and DNA barcodes
A study of alpine tortricid moths used male anatomy, DNA barcodes and museum specimens to distinguish Dichrorampha velata from D....
Radiation suppresses PiC, triggering mitochondrial dysfunction and glioma cell death
A mechanistic study in glioma cells and mouse tumor models links radiation-induced PiC suppression to mitochondrial dysfunction, sustained pore opening,...
Uncultured Gut Microbes Offer Obesity Leads, Not Yet Causal Answers
A 2026 review finds that multi-omics can generate testable hypotheses about uncultured gut microbes in obesity, but taxon-resolved experiments are...
Routine monitoring rediscovers Switzerland’s tiny Stactobia caddisfly
A routine monitoring sample confirmed the presence of the minute caddisfly Stactobia eatoniella in Valais in 2020, more than 70...
Targeting pyroptosis in intestinal and systemic inflammatory diseases: mechanisms and therapeutic opportunities
A 2026 review identifies pyroptosis as a context-dependent pathway in intestinal and systemic inflammation and evaluates inflammasome, caspase and gasdermin-directed...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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