Cryo-EM reveals how Andes hantavirus grips its human cell receptor
A new Nature study shows that the Andes virus spike captures the PCDH1 receptor through a deep central pocket that ...
Tag: structural biology
$16.4 Million NIH Award Launches Multi-Institution Center for Hepatitis C Vaccine Design
The NIH has awarded $16.4 million over five years to a new multi-institution U19 center led by Scripps Research to ...
PyMOL plugin brings protein circuit topology into the molecular viewer
An open-source PyMOL plugin integrates protein circuit topology analysis, visualization, trajectory processing and compaction scoring into an interactive molecular-viewing workflow.
Inside the Molecular Cities of Bacteria: New Imaging Reveals How Cellular Factories Work Together
Two new cryo-electron tomography studies from EMBL Heidelberg reveal how protein production, transport, and folding are interconnected in bacterial cells, ...
How Seven Tiny Mutations Break a Metabolic Enzyme and Cause a Rare Brain and Heart Syndrome
New crystal structures and biochemical analyses reveal that seven disease-causing SHMT2 mutations sabotage the same mitochondrial enzyme through strikingly different ...
Molecular Measuring Tape: How Plants Measure Fungal Signals to Tell Friend from Foe
Researchers at Aarhus University have discovered that a plant receptor called CHIP13 acts as a molecular measuring tape, using a ...
RFdiffusion3 designs proteins and nucleic acids atom by atom with striking precision
The new generative AI system RFdiffusion3 designs proteins and nucleic acids atom by atom, producing functional enzymes and RNA molecules ...
New RNA structure toolkit picks winning 3D models from eleven predictors
A new open-source framework called ROMET-RNA benchmarks eleven RNA 3D structure predictors and three alignment pipelines, using a consensus scoring ...
Hybrid docking-assembly algorithm cracks the structures of giant protein complexes
A new hybrid framework called HDOCK-Multimer combines protein-protein docking with combinatorial assembly to predict the structures of large protein complexes ...
Opioid drugs reach deep into their G proteins, single-molecule study reveals
Single-molecule FRET imaging shows that opioid ligands allosterically tune the conformational dynamics of bound G proteins over 70 angstroms away, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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