Tag: structural biology

Cryo-EM structures of the essential Candida albicans enzyme Chs1 reveal that a small-molecule inhibitor jams the chitin translocation channel, a ...

Three independent structural studies reveal that the plant receptor NUT recognizes the disulfide-locked cyclic loop of SCREW phytocytokines and recruits ...

A systematic benchmark across sample complexities shows the non-cleavable cross-linker DSS outperforms cleavable DSSO for most cross-linking mass spectrometry experiments, ...

Researchers have engineered S1.0, a ribosome-display synthetic nanobody library that yields high-affinity binders compatible with the Legobody cryo-EM toolkit without ...

Cryo-electron microscopy structures of the Mycobacterium tuberculosis DprE1–DprE2 epimerase complex reveal its tetrameric architecture and the precise binding modes of ...

Researchers have directly observed, at molecular resolution, how individual proteins self-assemble into a virus-like particle, revealing a finely tuned nucleation-and-growth ...

New research reveals that a single disulfide bond imposes the three-dimensional fold CTNIP4 needs for recognition by the plant immune ...

Researchers have launched AASIA, the first structure-informed protein interaction database covering chickens, ducks, pigs, cattle, and sheep with over 410,000 ...

Researchers have designed new protein subunits that integrate with a natural nanopore to create semisynthetic conduction pores with confirmed lumen ...

Ciapponi and colleagues have determined the cryo-EM structure of the canonical PRC1 holocomplex, revealing how its architecture coordinates assembly, H2A ...