Tag: structural biology

Cryo-EM structures of human NLRP6 in ATP-bound and unbound conformations reveal how ATP serves as an endogenous inhibitor of inflammasome ...

A Cell Research review synthesizes structural and mechanistic insights into inflammasomes and PANoptosomes, revealing how innate immune sensors assemble inflammatory ...

MemBrain v2 delivers an end-to-end, deep-learning-powered workflow for segmenting membranes and mapping membrane proteins in cryo-electron tomography across diverse datasets.

Cryo-electron microscopy reveals that repositioned polyubiquitin chains outside the ordered core can remodel tau fibril ultrastructure and shift the protofilament ...

Paired structural snapshots of GPR84 in different conformational states, combined with immune cell assays, reveal how ligands activate, block or ...

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms. Crystallization enables scientists ...

In a groundbreaking study, researchers from UC San Diego and the University of Texas Southwestern Medical Center have unveiled the ...

For decades, scientists have grappled with the intricacies surrounding filopodia, the slender, finger-like protrusions extending from cell membranes and playing ...