Growing Eye Cells in 3D Reverses Aging and Restores Their Healing Power
A three-dimensional Matrigel culture system reverses replicative aging in human limbal niche cells by upregulating the transcription factor FOSL1, which ...
Tag: mitochondria
Aging Muscle Weakens When a Key Exercise Enzyme Stays Switched On
New research in Aging Cell shows that the exercise-responsive enzyme CaMKII, when chronically activated, drives mitochondrial mislocalization, aging-like gene expression, ...
CoQ10 Fails to Deliver a Performance Edge for Athletes, Major Meta-Analysis Finds
A systematic review and meta-analysis of 24 randomized trials finds that coenzyme Q10 supplementation shows no robust overall benefit for ...
Mitochondrial Calcium Influx Powers the Dopamine Surge That Drives Drug Addiction
A new Nature Neuroscience study shows that opioids and methamphetamine, unlike natural rewards, drive mitochondrial calcium influx through the MCU ...
Zinc-Myricetin Nanoshell Rewires Mitochondria and Immunity to Repair Spinal Cord Injury
A lesion-responsive core-shell nanoparticle combining astaxanthin, a ZIF-8 framework, and a zinc-myricetin shell remodels mitochondrial and immune signaling to promote ...
Too Much Cysteine Kills Cells Through a Hidden Iron Overload in Mitochondria
A new Nature Metabolism study shows that excess cysteine kills cells by mobilizing ferritin iron, overloading mitochondria and collapsing iron–sulfur ...
Two-Timing Nanomedicine Rewires Heart Metabolism After a Heart Attack
Researchers developed a staged-release nanomedicine that coordinates early NAD+ replenishment with prolonged mitochondrial regulation to limit damage and preserve heart ...
Iron-Linked Cell Death May Explain Why Autism Risk Hits Male Mice Harder
A new mouse study links prenatal valproic acid exposure to ferroptosis-related brain damage that is more severe in males and ...
Synaptic Mitochondria May Explain Why Some Aging Brains Lose Mental Flexibility
Aging Cell study shows that oxidative stress in synaptic mitochondria of the medial prefrontal cortex underlies individual variability in age-related ...
Too Much Cysteine Comes at a Cost: Surplus Amino Acid Triggers Deadly Iron Overload in Cells
A new Nature Metabolism study shows that excess free cysteine disrupts mitochondrial iron homeostasis and triggers a distinct iron-dependent cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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