Iron Overload, Ferroptosis and the Liver: Mapping a Deadly Network
A new review maps how disrupted iron homeostasis and ferroptosis drive liver disease, from hereditary hemochromatosis to hepatocellular carcinoma, and ...
Tag: Hepcidin
Iron Levels Shift in Fatty Liver Disease, but Fibrosis Link Stays Unclear
A prospective case-control study of 60 Egyptians found that patients with metabolic dysfunction-associated fatty liver disease had higher ferritin and ...
Dialysis-Based Iron Removal Shows Feasibility in Pig Model of Sepsis-Linked Kidney Injury
A pilot study in three pigs found that a chelating polymer added to dialysate could extract labile iron during continuous ...
Iron paradox found in primary sclerosing cholangitis patients
A study of 60 PSC patients found elevated circulating iron, depleted liver iron stores, and increased hepcidin, revealing an atypical ...
Acid-Blocking Drug Plus Iron Chelator Shows Added Effect on Iron Overload in Hereditary Anaemias
A re-analysis of a placebo-controlled cross-over trial suggests that combining the proton pump inhibitor esomeprazole with the iron chelator deferasirox ...
Small comparative study links elevated hepcidin to untreated Graves’ disease in children
A comparative study of 42 children found higher hepcidin, ferritin, inflammation and antibody levels and lower serum iron in untreated ...
Gut Bacterium Prevotella copri Worsens Iron Overload in β-Thalassemia by Activating JAK/STAT Pathway
A new mouse study shows that the gut bacterium Prevotella copri worsens iron overload and chronic inflammation in β-thalassemia by ...
How a Cellular Fuel Sensor Helps Red Blood Cells Survive Anemia
A new study reveals how the energy sensor AMPK stabilizes the oxygen-responsive protein HIF-2α to drive red blood cell maturation ...
Kidney Disease in Newborn Mice Drives Iron Buildup in the Developing Brain
A new mouse study shows that severe kidney disease in newborns causes iron to accumulate throughout the developing brain, offering ...
Iron’s Master Switch: How Cells and the Body Keep the Perfect Balance
A new review maps the molecular circuits, from intracellular IRE-IRP sensors to the liver hormone hepcidin, that keep the body's ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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