How Pancreatic Cancer Cells Survive Detachment: Autophagy Emerges as Key to Spread
Researchers at Lund University have shown that pancreatic cancer cells engineered to survive detachment consistently switch on autophagy and ubiquitin ...
Tag: autophagy
Two Genes Team Up to Paint Barley Leaves in White and Green
German researchers have shown that white-striped leaves in an EMS-mutagenized barley line arise only when recessive mutations at two epistatic ...
Ancient Growth-Control Pathway Emerges as a Master Switch of Brain Ageing
A new review in Biogerontology argues that the Hippo–YAP/TAZ signalling pathway acts as a central hub linking brain ageing, neurodegeneration, ...
Ginseng Fights Fatigue by Switching Off Runaway Autophagy in Muscle Cells
A new mouse study shows that Panax ginseng relieves fatigue by reactivating the PI3K/AKT/mTOR pathway to suppress excessive autophagy and ...
Scientists Uncover Hidden Protein Driver Behind Scarring Kidney Disease
New research reveals that the protein Annexin A1 drives kidney fibrosis by activating YAP signaling and suppressing autophagy in renal ...
Bats and Whales Age Differently: Genomes Reveal Two Separate Roads to Long Life
A new comparative genomic study finds that small long-lived mammals like bats rely on DNA repair and autophagy while large ...
Damaged Mitochondrial DNA Emerges as a Central Driver of Pulmonary Arterial Hypertension
A new review argues that oxidized mitochondrial DNA acts as both a persistent inflammatory signal and a potential biomarker driving ...
Hidden RNA switches that control the cellular recycling behind bone loss
A new review maps how microRNAs, long non-coding RNAs and circular RNAs tune autophagy in bone cells, opening a fresh ...
Circular RNA Culprit Behind Imatinib Failure in Leukemia Identified
Researchers in China have identified a circular RNA, hsa_circ_0029325, that drives imatinib resistance in chronic myeloid leukemia by upregulating the ...
Gut Cancer Gene GLIS3 Found to Fuel Tumors Through a Vitamin B6 Enzyme and Autophagy
Researchers in China have shown that the transcription factor GLIS3 drives gastric cancer progression by binding to the PNPO promoter ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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