Berberine Emerges as a Candidate Multi-Target Modulator of Immune Aging
A new review in Biogerontology critically evaluates berberine and its derivatives as multi-target candidates for modulating immunosenescence, the age-related decline ...
Tag: autophagy
Hidden Protein Bosses the Cleanup Crew That Keeps Lupus at Bay
Scientists have discovered that the protein FAM76B regulates macrophage clearance of dying cells through an m6A-ISG15-autophagy pathway whose failure drives ...
AI Uncovers Hidden Human Protein That Builds Bridges Between Cells
Researchers used artificial intelligence to identify a previously unexplored human protein, TM184C, revealing a new mechanism of resource exchange and ...
Ubiquitin Enzyme UBE2N Emerges as Master Switch Between Liver Repair and Damage
A new Nature Metabolism study identifies the ubiquitin-conjugating enzyme UBE2N as the molecular switch that determines whether hepatocytes undergo protective ...
Long-Read Sequencing Unlocks Rare Genetic Cause of Inherited Ataxia
Researchers used long-read genome sequencing and RNA analysis to diagnose a rare hereditary ataxia caused by biallelic VPS41 variants, expanding ...
Newly Identified GPCR-Like Protein TM184C Controls Cellular Exchange and Autophagy
Researchers have identified TM184C as a GPCR-like protein that regulates both intercellular material exchange and autophagy, linking two fundamental membrane-based ...
Autophagy Protein AMBRA1 Unlocks NLRP3 Inflammasome Activation
Researchers have discovered that the autophagy protein AMBRA1 directly binds and allosterically opens the autoinhibited NLRP3 inflammasome, revealing a new ...
Breakthrough Discoveries Illuminate Cellular Health: Unveiling the Recycling Mechanism within Cells
Recent research from the Tata Institute of Fundamental Research in Mumbai, India has shed light on an essential cellular process ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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