Diabetes Drugs May Ease Pulmonary Hypertension by Taming Activin A Signaling
A new study links SGLT2 inhibitor therapy with reduced circulating activin A, improved right-heart function, and modulation of BMP/activin signaling ...
Tag: autophagy
Blocking a Single Protein Makes Childhood Cancer Cells Easier for Immunotherapy to Find
Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...
Hidden Protein Networks Emerge as Central Players in Huntington’s Disease
A new review argues that Huntington's disease is driven by widespread disruptions of interconnected protein networks, pointing to hub proteins ...
Cellular Recycling Machine Linked to Male Fertility Hormone Control
New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...
Bladder Cancer Breakthrough: BH3 Mimetics Make Cisplatin Deadly Again
New research shows that BH3 mimetic drugs targeting antiapoptotic Bcl-2 family proteins can sensitize bladder cancer cells and patient-derived tumor ...
Brief Vaping Exposure Leaves Lasting Damage in the Lung’s Deepest Tissue, Study Finds
A new study in JCI Insight shows that just days of e-cigarette vapor exposure damages the human distal lung, with ...
Calpain Blocker Restores Cellular Cleanup Crew and Protects Blood Vessels in Diabetes
A new study shows that overactivated calpains block autophagy and mitophagy in endothelial cells under high glucose, and that inhibiting ...
Cellular Freight Protein YKT6 Emerges as a Driver of Lung Cancer Growth
A new study finds that the vesicle-trafficking SNARE protein YKT6 is overexpressed in lung cancer, where it drives proliferation and ...
Plateau Fish Rewire Their Immune Systems to Survive Oxygen Starvation
A new genomic study reveals that the Tibetan plateau fish Gymnocypris eckloni deploys distinct immune strategies against severe short-term and ...
Scientists Map the Iron Recycling Switch That Decides Whether Cells Live or Die
A new review in the Journal of Translational Medicine maps how NCOA4-mediated ferritinophagy controls iron release and ferroptosis, cataloguing small-molecule ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!