Scientists Discover the Metabolic Enzyme That Turns Inflammation Into Muscle Wasting
A new Aging Cell study reveals that the inflammatory cytokine TNF-α drives muscle wasting in COPD by activating a p53-Prodh2-mitochondrial ...
Tag: mitochondrial DNA
How Tumor Mechanics Control Whether Mitochondrial DNA Fuels or Fights Cancer Immunity
A new review in the Journal of Translational Medicine proposes that the physical mechanics of solid tumors govern whether mitochondrial ...
Single Mutation, Many Faces: Study Maps Mitochondrial Disease in Chinese Children
A study of eleven Han Chinese children with the m.3243 A>G mitochondrial DNA mutation reveals striking phenotypic variability, a mean ...
Uncle’s DNA Mimicked a Parent–Offspring Match, Forensic Case Reveals
An Israeli forensic case shows how a maternal uncle's DNA produced a misleading parent–offspring signal in familial database searching until ...
Leaking Mitochondrial DNA Emerges as a Central Engine of Cellular Aging
A new review in Biogerontology argues that leaking mitochondrial DNA activates the cGAS-STING innate immune pathway in senescent cells, sustaining ...
New Algorithm Fills the Gaps in Evolutionary Distance Matrices with Tree-Aware Precision
Researchers have developed Hyb-Adam-UA, a two-stage algorithm that fills missing entries in mitochondrial DNA distance matrices by optimizing tree-like additivity, ...
Long and Short DNA Reads Join Forces to Sharpen Forensic Mitochondrial Profiling
A pedigree-based study of 177 individuals shows that nanopore long-read sequencing and Illumina short-read sequencing each excel at different forensic ...
Genetic Sleuthing Reveals Hidden Wildcat Lineages in Italy’s Apennine Mountains
A new study combining species distribution modelling and mitochondrial DNA analysis maps suitable habitat for the European wildcat across Italy ...
How Failing Cellular Housekeeping Fuels Brain Disease Through a Viral Alarm System
A new review in the Journal of Translational Medicine details how impaired mitophagy allows mitochondrial DNA to trigger cGAS–STING-driven neuroinflammation ...
Coral Genes Reveal a Hidden Map: Environment Splits Reef Populations at Small Scales
New research in the Gulf of California shows that a brooding coral's mitochondrial genes diverge with seafloor community differences at ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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