Intermittent Fasting Shows Early Promise Against Huntington’s Disease in First Human Trial
A 12-week pilot trial found that an eight-hour time-restricted eating window was feasible, well tolerated, and associated with favorable clinical ...
Tag: metabolism
Too Much Cysteine Comes at a Cost: Surplus Amino Acid Triggers Deadly Iron Overload in Cells
A new Nature Metabolism study shows that excess free cysteine disrupts mitochondrial iron homeostasis and triggers a distinct iron-dependent cell ...
Time-Restricted Eating Shows Early Promise in Huntington’s Disease Pilot Trial
A 12-week pilot study found that time-restricted eating was feasible and well tolerated in 20 people with early-stage Huntington's disease, ...
Ketone Bodies That Never Fall: A Warning Sign for Failing Hearts
Repeated blood measurements show that persistently elevated ketone bodies independently predict death and rehospitalization in heart failure patients across two ...
Cold-Activated RNA Eraser Switches On Fat Burning Beyond UCP1
A new Nature Metabolism study shows that the cold-activated RNA demethylase ALKBH5 stabilizes CKB mRNA to drive UCP1-independent, creatine-based heat ...
Hidden Chemical Variation in Cotton Hydrolysates Shapes Antibody Yields in Cell Culture
Chemometric analysis of cottonseed hydrolysates reveals that batch-to-batch chemical variability significantly influences CHO cell culture longevity, antibody productivity, and antibody ...
Immune Enzymes from Neutrophils Block Thermogenic Rewiring of Visceral Fat
A new Nature Metabolism study shows that neutrophil-derived serine proteases actively block the thermogenic beiging of visceral fat, explaining why ...
Metabolic Weaknesses Exposed in Prostate Cancer That Resists Enzalutamide
Multi-omic profiling of enzalutamide-resistant prostate cancer cells has revealed rewired lipid, glutamine and mitochondrial metabolism that creates druggable vulnerabilities and ...
Metabolism Holds the Key to the Senescence Secretome
A Cell Research perspective argues that cellular metabolism acts as the licensing mechanism that determines the composition and intensity of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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