TGF-β Suppresses Glycolytic Enzyme PFKM, Fueling Metabolic Shift and EMT in Lung Cancer
A new study shows that TGF-β-driven PFKM downregulation reroutes glucose toward glycogen storage and promotes invasive, mesenchymal-like behavior in lung ...
Tag: glycolysis
Long Noncoding RNA CYP4A22-AS1 Drives Radioresistance in Cervical Adenocarcinoma
A long noncoding RNA called CYP4A22-AS1 promotes radioresistance in cervical adenocarcinoma by shuttling YBX1 into the nucleus to activate the ...
Senescent Lymph Node Fibroblasts Block Human B Cell Proliferation Through Cell–Cell Contact
Laboratory experiments with human tonsil-derived fibroblasts show that senescent lymphoid stromal cells suppress B cell proliferation through contact-dependent mechanisms despite ...
Multi-omics maps carbon metabolism’s staged handoff as rice seeds germinate
An integrated multi-omics study of rice seed germination reveals a three-phase carbon metabolism program, from β-amylase-driven starch hydrolysis to sucrose ...
GSTK1 Ties Inflammation, Glycolysis, and Lactylation in Gastric Cancer
Integrated transcriptomic and cell-line analyses link GSTK1 expression to favorable gastric cancer prognosis and to IL-6/JAK2/STAT3 signaling, glycolysis-related proteins, and ...
Research report: Hypoxia-induced GP73 promotes the Warburg effect in hepatocellular carcinoma via HIF-1α
A cell and patient-cohort study links hypoxia-induced GP73 to HIF-1α-dependent glycolysis, growth, invasion and markers of transarterial chemoembolization resistance in ...
Multi-omics study links ILA to boosted duckweed growth in laboratory culture
A multi-omics culture study found that 100 micromolar indole-3-lactic acid promoted Lemna aequinoctialis growth and altered metabolites, lipids, gene expression, ...
Review Maps Metabolic Targets Across Pulmonary Fibrosis Cell Types
A 2026 review maps altered glucose, lipid and amino-acid metabolism across four major lung cell populations and identifies promising but ...
Cold-exposed frog livers rewire metabolism toward glucose production and fat storage
A five-day cold exposure at 5 °C triggers hyperglycemia and a coordinated transcriptional shift in the Xenopus laevis liver toward ...
Blood proteins reveal right ventricular remodeling after tetralogy of Fallot repair
A small proof-of-concept study found that adolescents with repaired tetralogy of Fallot and moderate-severe right ventricular dilation on cardiac MRI ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!