Single Genetic Change May Strike Twice in Rare Anemia Case, Long-Read Study Suggests
Long-read multi-omics sequencing of a severe GPI deficiency case has uncovered a candidate dual-effect variant that may simultaneously destabilize an ...
Tag: glycolysis
How Silicon Helps a Hardy Millet Beat Salt Stress at the Gene Level
A transcriptomic study reveals how silicon supplementation reprograms antioxidant defense, carbon metabolism and hormone biosynthesis to help finger millet tolerate ...
RNA Tagging Machine Behind Endometriosis Blood Vessel Growth Revealed
Scientists have identified how the m6A reader protein YTHDF3 boosts PFKFB3 translation to fuel the pathological angiogenesis that sustains endometriosis ...
Hidden Protein Brake on Plaques Reveals New Path Beyond Cholesterol
Researchers in Shanghai have discovered that the protein TXNIP suppresses dangerous plaque angiogenesis by degrading the glycolytic enzyme HK2 and ...
Cellular Recycling Switch SIRT1-FOXO1 May Hold Key to Taming Brain Inflammation
New research shows that the SIRT1-FOXO1 signaling axis acts as a molecular brake on excessive mitophagy and glycolytic metabolism in ...
Two-Timing Nanomedicine Rewires Heart Metabolism After a Heart Attack
Researchers developed a staged-release nanomedicine that coordinates early NAD+ replenishment with prolonged mitochondrial regulation to limit damage and preserve heart ...
Motor Protein KIFC1 Fuels Cervical Cancer Radioresistance Through a Splicing-Driven Glycolytic Switch
New research reveals that the motor protein KIFC1 drives cervical cancer radioresistance by shuttling the splicing factor SRSF3 into the ...
Mitochondrial Citrate Transporter SLC25A1 Drives Skin Cancer Through Histone Acetylation
Researchers in China have shown that the mitochondrial citrate transporter SLC25A1 promotes cutaneous squamous cell carcinoma by boosting histone H3 ...
Deleting a Detox Enzyme Shields Mouse Livers From Fat but Worsens Blood Sugar
New research in mice shows that deleting the glyoxalase 1 gene protects the liver from fat accumulation on a high-fat, ...
Neurexophilin 4 Emerges as a Molecular Driver of Kidney Cancer Through PI3K/AKT-Controlled Glycolysis
New research reveals that the protein neurexophilin 4 drives the growth, invasion and metabolic reprogramming of clear cell renal cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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