Mitochondrial Citrate Transporter SLC25A1 Drives Skin Cancer Through Histone Acetylation
Researchers in China have shown that the mitochondrial citrate transporter SLC25A1 promotes cutaneous squamous cell carcinoma by boosting histone H3 ...
Tag: glycolysis
Deleting a Detox Enzyme Shields Mouse Livers From Fat but Worsens Blood Sugar
New research in mice shows that deleting the glyoxalase 1 gene protects the liver from fat accumulation on a high-fat, ...
Neurexophilin 4 Emerges as a Molecular Driver of Kidney Cancer Through PI3K/AKT-Controlled Glycolysis
New research reveals that the protein neurexophilin 4 drives the growth, invasion and metabolic reprogramming of clear cell renal cell ...
Tiny Micropeptide Blocks Vascular Calcification by Tagging PKM2 for Destruction
A newly identified micropeptide called PKM2 AP inhibits vascular calcification by acting as a molecular glue that triggers ubiquitin-mediated degradation ...
Thyroid Cancer Protein Rewires Tumor Metabolism and Drives Drug Resistance
New research shows the protein ECT2 drives papillary thyroid carcinoma growth by suppressing lipoic acid metabolism, activating PI3K/AKT signaling and ...
Glycolytic Enzyme Accelerates ALS by Fueling Inflammatory Neuron Death
New research shows that loss of TDP-43 in ALS drives the glycolytic enzyme ALDOA to trigger inflammatory pyroptotic death of ...
PGAM1 Links Glycolysis and Autophagy to Control Growth and Stress Resilience
A familiar enzyme at the center of cellular energy production has been found to perform a second, unexpectedly powerful job: ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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