Copper Cell Death Emerges as a Hidden Driver of Acute Kidney Injury
A new study identifies cuproptosis as a major regulated cell death pathway in ischemic acute kidney injury and shows that ...
Tag: cell death
Tiny Protein G0S2 Emerges as a Master Switch for Cell Death in Liver Cancer
A new proteomic study reports that the small protein G0S2 promotes apoptosis through the BAX/Caspase3 pathway, positioning it as a ...
Crushed by Crowding: Tumor Pressure Triggers Cancer Cell Self-Destruction, Study Finds
New research shows that sustained mechanical confinement inside densely packed tumors activates necroptosis in migratory cancer cells, halting metastasis and ...
Chemical Tag on RNA Helps Melanoma Dodge Ferroptosis, Study Finds
New research shows that the m6A reader protein YTHDF2 promotes melanoma progression by destabilizing HMOX1 mRNA and shielding tumor cells ...
Betel Nut Chemical Shields Oral Cancer Cells From Copper-Driven Cell Death
New research shows that arecoline, the main alkaloid in betel nut, activates a ROS-NRF2-MT2A signaling axis that protects oral squamous ...
Copper Cell Death Pathway Uncovered as Driver of Blindness-Causing Retinal Injury
A new study in Cell Death Discovery shows that the copper-binding protein metallothionein 3 regulates cuproptosis in retinal ischemia–reperfusion injury ...
Diabetes Drug Metformin Surprisingly Blocks Ferroptotic Cell Death in Cancer Cells
New research shows that metformin and phenformin suppress cysteine deprivation-induced ferroptosis in cancer cells by dampening mitochondrial hyperpolarization, oxygen consumption, ...
Triaptosis: Scientists Unveil a New Form of Cell Death Centered on Endosomes
A new review in Cell Death & Discovery proposes triaptosis, an endosome-centered form of ROS-regulated cell death driven by oxidative ...
Trojan Horse Inhibitors Slip Through Gasdermin Pores to Shut Down Pyroptosis
New research shows that gasdermin D pores formed during pyroptosis can admit selectively designed caspase inhibitors, allowing the inflammatory cell ...
Spermidine Shields Ovarian Cells From Copper-Triggered Cell Death, Study Finds
New research shows that the natural polyamine spermidine protects pig ovarian granulosa cells from copper overload-induced cuproptosis by suppressing miR-194a-5p ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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