Proteasome Inhibition Eases Proteinuria in Mice With Faulty Kidney Filtration Genes
Blocking the proteasome reduces protein leakage in the urine of mice carrying dysfunctional Lmx1b LIM domains, pointing to a new ...
Master Switch Silenced: Distant DNA Element Holds Human Regulatory T Cells on Their Anti-Inflammatory Path
Researchers have identified a distal IRF4 chromatin regulatory element as the genomic control point that permits inflammation-induced reprogramming of human ...
New Wood-Rotting Mushroom Species Unearthed in Pakistan’s Himalayan Foothills
Mycologists in Pakistan have described Stropharia khanspurica, a new wood-rotting mushroom species from Khanspur, identified through its distinctive morphology and ...
Tiny RNA Fragment in Sperm Tracks Severity of Varicocele-Linked Infertility
Researchers report the first evidence that sperm tRNA-derived fragments are altered in varicocele, with tRF-36 significantly downregulated in the most ...
Prostate Cancer Screening Gaps Between Rural and Urban America May Be Smaller Than Feared
A new national analysis of more than 15,000 older American men finds no significant rural–urban disparities in PSA testing or ...
Cancer Cells Rewire Their Fuel Supply When This Growth Signal Switches On
New research reveals that HGF/c-MET signaling reprograms glutamine metabolism in MET-amplified head and neck cancer cells through ERK-dependent induction of ...
Iron-tin dual-atom catalyst shields seawater batteries from chloride attack
Researchers at Hainan University have designed an iron-tin dual single-atom catalyst that accelerates oxygen reduction in alkaline seawater while blocking ...
MRI, Genes and Single-Cell Data Point to Vulnerable Brain Regions in ALS
By integrating MRI, brain-wide gene expression and single-cell sequencing, researchers have identified MOBP and ZNHIT3 as candidate genes underlying region-specific ...
Hybrid AI Model Predicts Heat-Stressed Dairy Cows’ Milk Yields With New Precision
A hybrid NARX–XGBoost machine learning framework predicts daily milk yields in heat-stressed dairy cows with substantially higher accuracy than existing ...
Flashover Uncovered: How Ancient Huizhou Walls and Skywells Reshape Fire Survival
A new study reveals how partition walls and skywell retrofits alter the critical mechanisms that trigger flashover in Huizhou's ancient ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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