Sugar Signature Reveals Which Tumor-Fighting T Cells Are Most Vulnerable
Researchers at Peking University have developed a single-cell method showing that low α2,6-linked sialylation marks the most potent tumor-reactive CD8+ ...
Tag: tumor microenvironment
Three Ways to Die: How Ferroptosis, Cuproptosis and Pyroptosis Shape Cancer
A new Molecular Cancer review proposes an "interconnected death" framework showing how ferroptosis, cuproptosis, and pyroptosis interact through shared metabolic ...
Hypoxia Rewires RNA Methylation to Drive Pancreatic Neuroendocrine Tumor Growth
A new study reveals how low oxygen strips m6A methylation marks from tumor cell RNA, unleashing a signaling cascade that ...
Genomic and Transcriptomic Landscape of Spread Through Air Spaces in Stage 1 Lung Adenocarcinoma
A new study maps the genomic and transcriptomic features of spread through air spaces in stage 1 lung adenocarcinoma, offering ...
Jumping Genes May Ignite Immune Defenses in Stomach Cancers with DNA Repair Weaknesses
New research links LINE-1 retrotransposon overexpression and homologous recombination deficiency in gastric cancer to heightened immune pathway activation and potential ...
Fibroblasts Recruit Antitumor B Cells in Liver Cancer, Study Finds
Spatial transcriptomic mapping of liver tumors has revealed that CCL19-producing fibroblasts recruit CXCR3-positive B cells to form an antitumor axis ...
Tumor Slice Cultures Reveal New Pitfalls in Testing AAV Gene Therapy for Glioblastoma
A new study shows that the choice of patient-derived culture model strongly shapes how AAV-mediated gene delivery performs in glioblastoma, ...
Engineered fusogenic vaccinia virus arms IL-15 to reprogram tumors and boost antitumor immunity
Researchers engineered a fusogenic oncolytic vaccinia virus that displays IL-15Rα on infected tumor cells to locally trans-present IL-15, reprogramming the ...
Lab-Grown Tumor Organoids Illuminate How Cancers Evade, Tolerate, and Resist Treatment
A new review in Molecular Cancer positions patient-derived organoids as living systems for mapping how cancers tolerate, persist through, and ...
Silenced APP Protein Reveals Why Pediatric Brain Tumors Hide From the Immune System
An integrated multi-omics study shows that mesenchymal-like tumor cells drive myeloid recruitment in pediatric high-grade glioma and that reduced amyloid ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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