Mirror-image molecules can modify signaling in neurons
With the aid of some sea slugs, University of Nebraska–Lincoln chemists have discovered that one of the smallest conceivable tweaks ...
Tag: signaling
Aging | The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans
“In this study, we found that DR prevents muscle aging via fbxc-58 in C. elegans.” Credit: 2023 Hahm et al. ...
Genes & Cancer | Slit2 signaling stimulates Ewing sarcoma growth
BUFFALO, NY- January 13, 2023 – A new research paper was published in Genes & Cancer on December 14, 2022, ...
Oncotarget | Calcium signaling induced by 15-deoxy-prostamide-J2 promotes cell death by activating…
“The goal of the present study was to determine the therapeutic potential of 15d-PMJ2 against melanoma by gaining insight into ...
Link between sphingolipids and complement signaling may be key to stopping cancer metastasis
MUSC Hollings Cancer Center researchers have identified the sequence of molecular interactions that could be key to stopping the spread ...
Oncotarget | The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies
“Pyrethroid derivatives and related products exposure have revealed to intensify various ailments and adverse health consequence in the different age ...
Oncotarget | Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer
“The present study analyzed PDGFR and VEGFR expression in primary colon cancer tissues and CRC cell lines in order to ...
More flexible than previously thought: Worms give us new insights into the evolution and diversification of TGF-β signaling pathways
Have you ever thought about what you have in common with tiny roundworms? As the “nematodes” are metazoan animals like ...
New published data point to spike protein interactions with estrogen receptors as a cause for coagulopathy in COVID-19 patients, signaling sex effects and a path to improved vaccines
Credit: Dompé farmaceutici A team of US and European researchers released new findings in Science Advances showing how the SARS-CoV-2 ...
Hippo signaling does not instruct normal organ growth
The Hippo signaling pathway – a genetic program thought to play a central role in organ development – does not ...
Switching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling
A group of researchers from the Helmholtz Munich Institute for Diabetes and Cancer (IDC) and the German Center for Diabetes ...
Short telomeres impede germ cell specification by upregulating MAPK and TGFβ signaling
Functional telomeres protect chromosome ends and play essential roles in stem cell maintenance and differentiation. Over the past decade, telomeres ...
Quantum-Si’s next-generation single-molecule protein sequencing technology published in Science, signaling new era of life science and biomedical research
GUILFORD, Conn. – Oct. 13, 2022 – Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a life sciences company commercializing ...
Unraveling the reward behavior: mechanisms underlying the dopamine signaling pathway
One part of the basal ganglia, known as the nucleus accumbens (NAc), is composed of medium spiny neurons (MSNs). The ...
Altered insulin signaling allows queen ants to live long and reproductively prosper
Altered insulin signaling in ant queens may endow them with their characteristic longevity, despite being a colony’s sole reproducers, researchers ...
New cryo-EM images taken at UTSW shed light on Wnt signaling
Credit: UT Southwestern Medical Center Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which ...
Oncotarget | A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
“These results increase our understanding of the signaling molecules that can regulate GLI3 in a HH-independent manner.” Credit: Matissek et ...
Signaling ‘stressed-out’ plants
A plant scientist from the University of Missouri has discovered a new way of measuring stress in plants, which comes ...
UCI-led team discovers signaling molecule that potently stimulates hair growth
Irvine, Calif., June 30, 2022 — University of California, Irvine-led researchers have discovered that a signaling molecule called SCUBE3 potently ...
Aging (Aging-US) sponsors 2022 NAD + Metabolism and Signaling Conference
BUFFALO, NY- June 21, 2022 – Aging (Aging-US) is proud to sponsor this year’s NAD + Metabolism and Signaling Conference ...
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Can AI predict how you’ll vote in the next election?
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Extinction of steam locomotives derails assumptions about biological evolution
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Ancient DNA reveals Asian ancestry introduced to East Africa in early modern times
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Unique image obtained by Brazilian scientists with high-speed camera shows how lightning rods work
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A final present from birds killed in window collisions: poop that reveals their microbiomes
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Cancer that spreads to the lung maneuvers to avoid being attacked by “killer” T cells