Tiny Micropeptide Blocks Vascular Calcification by Tagging PKM2 for Destruction
A newly identified micropeptide called PKM2 AP inhibits vascular calcification by acting as a molecular glue that triggers ubiquitin-mediated degradation ...
Tag: protein degradation
Ufd1 Unfolds Ubiquitin Without ATP to Kick-Start Cdc48/p97 Waste Disposal
A small domain of the cofactor Ufd1 unfolds K48-linked ubiquitin without ATP by cooperatively binding two ubiquitin molecules, providing the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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