Tag: preclinical study

A synthetic antimicrobial peptide called SK1217 suppressed autoantibodies, cytokines, BAFF-driven B cell activation, and kidney damage in a pristane-induced lupus ...

A new rat study shows that the antidepressant agomelatine suppresses nicotine-induced locomotor sensitization, pointing to a possible repurposing strategy for ...

A dual-photosensitizer light treatment combined with optical clearing eradicated thick pigmented melanoma in mice by triggering a potent, long-lasting anti-tumor ...

A novel intravenous STING agonist, BI 1703880, synergises with radiotherapy and checkpoint inhibitors to generate durable anti-tumour immunity in preclinical ...

A University of Cincinnati and UC Davis team showed that an AAV gene therapy targeting cerebrospinal fluid-producing cells reduced hydrocephalus-related ...

Researchers have developed an optimized tumor-infiltrating lymphocyte manufacturing protocol that shows preclinical efficacy against NF1- and schwannomatosis-related nerve sheath tumors, ...

A Duke University preclinical study finds that the experimental ATM inhibitor AZD1390 reduced stroke-related brain injury in mice only when ...

Researchers report that adding interleukin-18 to cultures of scarce human Vδ1 T cells boosts their expansion, survival and antitumor performance ...

Scientists have engineered a bispecific antibody that simultaneously blocks TL1A and IL-12/23p40, suppressing pathogenic Th1/Th17 immune responses and significantly ameliorating ...

Oregon State University researchers have shown in mice that cobalt-doped iron oxide nanoparticles can both reveal a misplaced placenta on ...