Grid-Shaped Radiation Beats Conventional Beams in Boosting CAR T Therapy for Brain Lymphoma
A rat study shows that spatially fractionated minibeam radiation, unlike conventional radiotherapy, preserves the efficacy of CD19-directed CAR T cells ...
Tag: preclinical study
Gallic Acid Shrinks Tumors in Mice While Sparing Blood Cells, Study Finds
A new preclinical study shows that orally delivered gallic acid significantly inhibited sarcoma tumor growth in mice by suppressing proliferation, ...
Two-Pronged Immunotherapy Strategy Cracks Glioblastoma’s Defenses in Preclinical Study
Wistar Institute scientists report that combining the kidney cancer drug axitinib with a 4-1BB agonist overcame myeloid cell suppression and ...
Mini-GRID Radiotherapy Curbs Cellular Senescence While Keeping Its Anti-Tumor Punch in Glioma Cells
A preclinical study finds that spatially fractionated mini-GRID radiotherapy preserves the growth-inhibitory effect of radiation in glioma cells while markedly ...
Blocking a Single Protein Makes Childhood Cancer Cells Easier for Immunotherapy to Find
Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...
mRNA Vaccine Paired With Radiotherapy Shrinks HER2-Positive Lung Tumors in Mice
A HER2-targeted mRNA lipid nanoparticle vaccine combined with fractionated radiotherapy suppressed tumor growth and reprogrammed the immune microenvironment in a ...
Ginseng and Ginger Combo Shields Mouse Stomachs From Stress-Induced Damage
A 3:1 ginseng-ginger extract reduced hemorrhagic gastric lesions, inflammation, and lipid peroxidation while boosting antioxidant defenses in a mouse model ...
Mushroom Compound Pachymic Acid Supercharges Lenvatinib Against Liver Cancer by Starving Tumors of Sugar
A new study shows that pachymic acid, a compound from the medicinal mushroom Poria cocos, synergizes with lenvatinib against hepatocellular ...
Engineered CAR-T Cells That Make Their Own IL-2 Show Stronger Staying Power Against Pancreatic Cancer
A preclinical study shows that CAR-T cells engineered to secrete an Fc-fused IL-2(C125S) variant persist longer, retain mitochondrial fitness, and ...
3D-Printed Bone-Anchored Prosthesis Shows Promise in Preclinical Tests
A 3D-printed osseointegration prosthesis featuring a cloverleaf sleeve showed superior stress distribution, stable fixation and favorable bone integration in preclinical ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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