Chemical Tag on mRNA Reveals Hidden Switch That Controls Hair Growth Cycles
A new PLOS Genetics study shows that the RNA modification enzyme METTL1 controls hair follicle cycling by stabilizing HOXC13 messenger ...
Tag: post-transcriptional regulation
Hidden RNA Switches in the Human Brain Reveal New Genetic Routes to Alzheimer’s and Parkinson’s Disease
A single-cell atlas of alternative polyadenylation across two million human brain cells reveals a hidden genetic regulatory layer that explains ...
Tiny RNA, Big Stakes: New miR65 Switch Governs How Alfalfa Survives Salty, Alkaline Soil
Researchers have identified a novel microRNA, miR65, that represses the transcription factor MsbZIP11 and acts as a key negative regulator ...
Fungal Killer’s Achilles Heel Found in RNA Splicing Machinery
A conserved Lsm8-exosome module that safeguards RNA splicing fidelity has been revealed as a master switch controlling growth, stress adaptation, ...
RNA-Destroying Enzyme Regnase-1 Emerges as a Master Switch in Autoimmune Disease
A new review in Molecular Biology Reports argues that the RNA-degrading enzyme Regnase-1 and its family members act as cell-type-specific ...
Hidden RNA Circles Help Rice Survive Heat and Drought Together
A new study maps 208 circular RNAs in rice and reveals a predicted regulatory network that may coordinate the crop's ...
Alcohol Withdrawal Reshapes RNA Binding of PCBP1 in the Hippocampus
A new RIP-Seq study reveals sex-dependent changes in how the RNA-binding protein PCBP1 associates with synaptic and myelination-related transcripts in ...
LncRNA AC040169.1 Enhances Ovarian Cancer via m6A Regulation
In the intricate realm of cancer research, the understanding of long non-coding RNAs (lncRNAs) has significantly evolved over the past ...
TDP-43 Loss Triggers Broad Polyadenylation Shifts in FTD/ALS
In a groundbreaking study published in Nature Neuroscience, researchers have unveiled that the nuclear depletion of the protein TDP-43 in ...
Achieving Harmony: Balancing the Immune System for Optimal Health
A groundbreaking study from the Babraham Institute has unveiled a pivotal role for the Zinc Finger Protein 36 (ZFP36) family ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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