The Phosphatase Switch: How PP2Acα Emerges as a Drug Target for Inflammatory Bowel Disease
A new review argues that the phosphorylation-dephosphorylation balance controlled largely by the phosphatase PP2Acα acts as a master switch in ...
Tag: NF-κB
Ancient Ayurvedic Formula Triphalaguggul Shows Potent Anti-Arthritis Action in Rat Study
A traditional Ayurvedic formulation called Triphalaguggul dramatically reduced inflammation and cartilage damage in rat models of osteoarthritis and rheumatoid arthritis ...
Leukemia Marker CD7 Revealed as Hidden Engine of Chemotherapy Failure
New research shows that the surface protein CD7 actively drives chemotherapy resistance in acute myeloid leukemia by amplifying NF-κB signaling, ...
Nanoparticle Citrus Flavonoid Shields Kidneys in Mice with Cancer, Study Finds
A new study in Medical Oncology reports that diosmin loaded into chitosan nanoparticles reduced tumor burden and protected the kidneys ...
How the Microbiome Shapes HPV Infection and Gynecological Cancer Risk
A new review synthesizes evidence that gut and vaginal microbiota dysbiosis promotes persistent HPV infection and the development of cervical, ...
Gallic Acid Shrinks Tumors in Mice While Sparing Blood Cells, Study Finds
A new preclinical study shows that orally delivered gallic acid significantly inhibited sarcoma tumor growth in mice by suppressing proliferation, ...
The Hidden Switch That Helps Breast Cancer Survive and Resist Treatment
A comprehensive new review maps how NF-κB signalling drives breast cancer progression, subtype-specific therapy resistance and tumour-microenvironment crosstalk, and argues ...
How a Common Grain Toxin Hijacks Cells—and How Probiotics Fight Back
A new review maps how the mycotoxin deoxynivalenol hijacks ribosomal and cellular signaling networks to drive intestinal, immune, neurological and ...
Interferon-Gamma Emerges as a Potential Hub Linking Inflammation to Fibrosis in Sjögren’s Lung Disease
A new review proposes that interferon-gamma acts as a regulatory hub connecting immune activation, inflammatory amplification, and fibrotic remodeling in ...
Stinky Leaf Plant Yields Tiny Nanoparticles Packed With Anti-Inflammatory Cargo
Researchers isolated exosome-like nanoparticles from the medicinal vine Paederia foetida and found they carry five anti-inflammatory terpenoids and 1,170 microRNAs ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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