FAERS analysis maps early, diverse ifosfamide neurological adverse events
A FAERS analysis of 786 ifosfamide-related neurological reports found a strong encephalopathy signal, a median onset of two days and ...
Tag: neurotoxicity
CAR T-Cell Therapy May Spare Older Patients’ Memory More Than Younger Ones
A longitudinal study of 155 lymphoma patients found that older adults recovered memory function after CAR T-cell therapy while younger ...
Global expert panel issues first consensus roadmap for brentuximab vedotin nerve damage
Brentuximab vedotin has transformed the outlook for patients with CD30-positive lymphomas, but the antibody-drug conjugate carries a neurological price that ...
Sea Urchins and Spheroids: How Ethical Models Are Rewriting Pesticide Toxicity Testing
A new review argues that a tiered panel of bioethical models, from human cell lines and neural spheroids to brine ...
AI Models Race to Predict Chemical Toxicity Before Drugs Reach Patients
A new review in Frontiers in Bioinformatics surveys how machine learning and deep learning models are reshaping toxicity prediction across ...
Microplastics Are Supercharging Toxic Pesticides in Farmed Fish, Review Warns
A new review finds that microplastics in aquaculture systems act as carriers for neurotoxic synthetic pyrethroids, reshaping how these pesticides ...
Low-Dose BCMA CAR-T Therapy Anito-Cel Eradicates Myeloma in All 38 Phase 1 Patients
A phase 1 trial found that the investigational BCMA-targeted CAR-T therapy anito-cel produced responses in all 38 participants with relapsed ...
Electric Fish Reveal Hidden Brain Side Effects of a Common Cough Suppressant
A new quadrimodal assay using weakly electric fish detected dose-dependent brain effects of dextromethorphan, offering drug developers an early warning ...
Delhi’s Finest Air Pollution Particles Show Where Toxic Metals Lodge in the Body
A new rat study shows that metals carried on Delhi's submicron air pollution particles accumulate in specific organs, with lead ...
Grid-Shaped Radiation Beats Conventional Beams in Boosting CAR T Therapy for Brain Lymphoma
A rat study shows that spatially fractionated minibeam radiation, unlike conventional radiotherapy, preserves the efficacy of CD19-directed CAR T cells ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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