Chronic Alcohol Disrupts Myelin-Making Brain Cells in Human Cerebellum, Study Finds
A postmortem study of human cerebellar tissue reveals that alcohol use disorder disrupts oligodendrocyte function, insulin/IGF-Akt signaling, and Notch pathway ...
Tag: neuroinflammation
Ancient Chinese Formula Shields the Brain by Rewiring Gut Microbes and Metabolism
A multi-omics study shows that the classical Chinese formula Xijiao Dihuang Decoction protects rats against stroke reperfusion injury by remodeling ...
Hidden Immune Overdrive in Blood Reveals Parkinson’s Patients Carrying Alzheimer’s Co-Pathology
A multidimensional immunological study of early-stage Parkinson’s disease uncovers a hyperinflammatory, hypermetabolic blood signature that separates patients with Alzheimer’s co-pathology ...
Cytokine-Driven microRNA Shifts in Brain Endothelial Cells Offer New Route to Protect the Blood-Brain Barrier
A new review shows how TNF-α and IFN-γ rewire microRNA profiles in brain endothelial cells, dismantling blood-brain barrier junctions and ...
Repurposed antimalarial drug wrapped in lactoferrin nanoparticles calms complement attack on motor nerves in ALS mice
A new preclinical study reports that atovaquone, an approved antiparasitic drug, was reformulated into lactoferrin-based nanomicelles that crossed into the ...
Astrocyte Gene ATP13A2 Revealed as a Hidden Brake on Brain Inflammation in Parkinson’s Disease
New research shows that the Parkinson's-linked gene ATP13A2 keeps astrocytic mitochondria in balance, and that its loss triggers excessive mitochondrial ...
DNA Nanosensors Paired With AI Aim to Catch Brain Inflammation Early
A new review in Results in Chemistry details how programmable DNA nanobiosensors combined with artificial intelligence could enable early detection ...
When a Fever Attacks the Brain and Heart: A Rare Childhood Syndrome Challenges Doctors
A case report from Tehran describes a four-year-old girl with acute necrotizing encephalopathy of childhood complicated by fulminant myocarditis, highlighting ...
Bipolar Disorder Reimagined: A Body-Wide Feedback Loop May Drive the Mood Cycle
A new integrative review proposes that bipolar disorder arises from a destabilized feedback network linking stress hormones, mitochondrial energy failure, ...
Spatial Niches May Explain Why Brain Implants Lose Their Signal Over Time
A new analytical framework proposes that spatial niches — recurring local cellular and molecular neighborhoods around implanted microelectrodes — could ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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