Glycolytic Enzyme Accelerates ALS by Fueling Inflammatory Neuron Death
New research shows that loss of TDP-43 in ALS drives the glycolytic enzyme ALDOA to trigger inflammatory pyroptotic death of ...
Tag: neuroinflammation
Intensive Care Survivors Face Long-Term Disability as Evidence on Rehabilitation Falls Short
A major narrative review finds that post-intensive care syndrome affects a large share of ICU survivors and their families, yet ...
Astrocyte Fibronectin Emerges as Key Driver of Blood–Brain Barrier Failure in Alzheimer’s Disease
A new Nature Aging study identifies astrocyte-derived fibronectin as the molecular link between the APOE ε4 allele, amyloid pathology, and ...
Omega Fatty Acid Supplements Fail to Ease Autism Behaviors in Rigorous Child Trial
A rigorous randomized controlled trial found that omega-3 and omega-6 supplementation did not reduce inflammatory cytokines or improve autism-related behaviors ...
Hidden Damage in the Brain’s Outer Layers Drives Multiple Sclerosis Progression
A 25-year review in Nature Reviews Neurology establishes cortical lesions as central drivers of multiple sclerosis progression, cognitive decline and ...
Prenatal Stress Leaves Lasting Cognitive Scars Through Brain Immune Protein Galectin-3
New research in rats shows that prenatal stress drives microglial Galectin-3 expression, fueling neuroinflammation and lasting cognitive impairment in adult ...
Reishi Mushroom Compounds Show Promise Against Age-Related Memory Decline in New Study
New research reports that Ganoderma lucidum polysaccharides ameliorate cognitive decline and neuroinflammation in aging by acting through a gut microbiome ...
Glucose-Lowering Drugs and Brain Health: Mechanisms, Evidence, and Future Directions
Scientists are taking a hard look at whether the world's most widely prescribed diabetes medications could do far more than ...
Immune receptor MARCO drives shingles virus brain inflammation
Varicella zoster virus, the neurotropic herpesvirus behind chickenpox and shingles, has long been known to hide silently in sensory neurons ...
M2-like microglia drive oligodendrocyte repair in vascular dementia
Every year, millions of people lose their memories, their reasoning and their independence to vascular dementia, the second most common ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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