Molecular mechanisms of programmed cell death in aortic dissection and advances in clinical translation
A 2026 review identifies multiple forms of programmed cell death as contributors to aortic dissection progression but finds limited clinical ...
Tag: matrix metalloproteinases
Review links bacterial inflammation, NETs and MMP activation to gallstone formation
A 2026 review synthesizes evidence linking biliary bacterial infection, NET formation, MMP activation, bile-acid toxicity and altered lipid metabolism to ...
Protease Inhibitors May Finally Crack Cancer’s Drug Resistance Problem
A new review argues that proteases drive chemoresistance through drug transport, matrix remodeling, and cell death signaling, and that precision-targeted ...
Early Aortic Valve Sclerosis Shows Active Inflammation and Matrix Breakdown
A cross-sectional study of 168 participants finds elevated MMP-9, reduced TIMP-1, and higher TNF in aortic valve sclerosis, defining an ...
Smart Microneedle Patch Uses Light and Cryptochlorogenic Acid to Quiet Joint Osteoarthritis
Researchers developed a near-infrared-responsive microneedle patch that delivers cryptochlorogenic acid via ZIF-8 nanoparticles to inhibit MMP3, MMP9 and MMP13 and ...
Tiny Messengers in Joint Fluid Calm Inflammation in Osteoarthritis Cells
Extracellular vesicles isolated from the synovial fluid of osteoarthritis patients reduce inflammatory and catabolic markers in joint cells while boosting ...
Stable Vitamin C Derivative Calms Inflammation and Boosts Collagen in Human Lung Cells
A stable vitamin C derivative reduced pro-inflammatory cytokines and increased collagen and hyaluronan synthase levels in human lung fibroblasts in ...
Sepsis May Leave Tissues Primed for Cancer, Review Argues
A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...
Transplant Drug Rewires Prostate Tissue in Two Distinct Phases, Rat Study Finds
A new rat study shows the immunosuppressant mycophenolate mofetil dismantles prostate stromal fibers in two timed phases, reshaping collagen, immune ...
Why Leg Veins Fail: New Review Maps the Hidden Mechanics of Chronic Venous Insufficiency
A new review in Annals of Biomedical Engineering maps the full pipeline from biaxial tissue testing and extracellular matrix architecture ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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