Iron, Lipids and Cell Death: Ferroptosis Biomarkers Emerge as Clues to Vitiligo Activity
A new case-control study finds that serum markers of ferroptosis, including ACSL4, MDA and ROS, are elevated in vitiligo vulgaris ...
Tag: lipid peroxidation
Scientists Uncover How Oral Cancer Cells Outsmart Cisplatin by Blocking Ferroptosis
New research reveals that the secreted protein DKK1 helps oral squamous cell carcinoma resist cisplatin by keeping the SLC3A2 cystine ...
Chemical Tag on RNA Helps Melanoma Dodge Ferroptosis, Study Finds
New research shows that the m6A reader protein YTHDF2 promotes melanoma progression by destabilizing HMOX1 mRNA and shielding tumor cells ...
Diabetes Drug Metformin Surprisingly Blocks Ferroptotic Cell Death in Cancer Cells
New research shows that metformin and phenformin suppress cysteine deprivation-induced ferroptosis in cancer cells by dampening mitochondrial hyperpolarization, oxygen consumption, ...
Stevia Extract Shields Diabetic Livers by Taming Iron-Driven Cell Death
A new rat study shows aqueous stevia extract protects diabetic livers by suppressing ferroptosis, boosting antioxidant enzymes, and reducing inflammation.
Copper Overload Silences a Key Liver Fat Gene, Pushing Cells Into Ferroptosis in Wilson Disease
New research shows that copper accumulation in Wilson disease shuts down the PPARα–FABP1 fat-handling axis in hepatocytes, sensitizing them to ...
Cholesterol Drug Alirocumab Shields the Heart From Alcohol Damage in Rat Study
A new GeroScience study shows that weekly alirocumab, an approved PCSK9 inhibitor, protected rats from alcohol-induced cardiac dysfunction, fibrosis, and ...
Iron-Powered Cell Death Emerges as Double-Edged Sword in Cancer’s Microenvironment
A new review in Medical Oncology maps how the tumor microenvironment can either amplify or suppress ferroptosis, the iron-dependent cell ...
Iron, Inflammation, and a Deadly Paradox: Rethinking Cancer Wasting Through Ferroptosis
A new iScience review argues that ferroptosis, an iron-driven form of cell death, links tumor and immune signals to muscle ...
Three Blood Biomarkers Together Predict ALS Progression and Survival, Study Finds
A longitudinal study of 100 ALS patients shows that combined serum levels of 4-HNE, LBP, and NfL discriminate rapid disease ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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