A Lipid Dial May Decide Whether Bile Duct Cancer Cells Live or Die by Ferroptosis
A new review proposes that the ratio of monounsaturated to polyunsaturated membrane phospholipids acts as a tunable rheostat controlling ferroptosis ...
Tag: lipid peroxidation
Longer Fat Chains, Shorter Lives: Lipid Elongation Emerges as a Hallmark of Aging
A Nature Aging commentary highlights research identifying lipid acyl-chain elongation as a conserved, causal and potentially reversible hallmark of aging ...
Splicing Factor LUC7L2 Emerges as a Driver of Kidney Damage from Chemotherapy
New research reveals that the RNA splicing factor LUC7L2 drives ferroptotic kidney damage from cisplatin by corrupting the splicing of ...
Glyphosate Weedkiller Hits Algae Harder Than Its Active Ingredient Alone, Study Finds
A new Argentine study shows that a commercial glyphosate-based herbicide is roughly seventy times more toxic to the freshwater alga ...
A Methylation Signature in Brain Fluid Predicts Who Survives a Deadly Stroke
Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...
Scientists Map the Iron Recycling Switch That Decides Whether Cells Live or Die
A new review in the Journal of Translational Medicine maps how NCOA4-mediated ferritinophagy controls iron release and ferroptosis, cataloguing small-molecule ...
Common Medicinal Herb Shields Rat Livers and Kidneys From Fluoride Damage
A new rat study shows that extracts of the medicinal herb Phyllanthus amarus restore antioxidant defenses and reduce DNA fragmentation ...
Ginseng and Ginger Combo Shields Mouse Stomachs From Stress-Induced Damage
A 3:1 ginseng-ginger extract reduced hemorrhagic gastric lesions, inflammation, and lipid peroxidation while boosting antioxidant defenses in a mouse model ...
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
Breast Cancer Drug Lapatinib Unexpectedly Shields Lung Cancer Cells From Ferroptosis
New research shows the breast cancer drug lapatinib protects lung cancer cells from cysteine starvation-induced ferroptosis by restraining mitochondrial metabolic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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