Cellular Death Switch Found: Fission Protein MFF Senses and Drives Ferroptosis
Researchers have identified mitochondrial fission factor as a phosphorylation-controlled switch that senses and drives ferroptosis, built a live-cell biosensor to ...
Tag: lipid peroxidation
Stem Cell Therapy Eases Crohn’s Disease by Blocking Iron-Driven Cell Death
New research shows mesenchymal stem cells relieve Crohn's disease in mice by upregulating the enzyme CBS, restoring antioxidant defenses and ...
Three Ways to Die: How Ferroptosis, Cuproptosis and Pyroptosis Shape Cancer
A new Molecular Cancer review proposes an "interconnected death" framework showing how ferroptosis, cuproptosis, and pyroptosis interact through shared metabolic ...
Zinc Finger Protein ZNF154 Pushes Bladder Cancer Cells Into Ferroptosis by Suppressing a Key Survival Pathway
Researchers show that the zinc finger protein ZNF154 suppresses bladder cancer by activating PTEN transcription, blocking PI3K/AKT signaling, and triggering ...
Iron-Linked Cell Death May Explain Why Autism Risk Hits Male Mice Harder
A new mouse study links prenatal valproic acid exposure to ferroptosis-related brain damage that is more severe in males and ...
Too Much Cysteine Comes at a Cost: Surplus Amino Acid Triggers Deadly Iron Overload in Cells
A new Nature Metabolism study shows that excess free cysteine disrupts mitochondrial iron homeostasis and triggers a distinct iron-dependent cell ...
Hidden RNA Switch Helps Esophageal Cancer Evade Ferroptotic Cell Death
A new study reveals that the m6A-stabilized long non-coding RNA SSTR5-AS1 helps esophageal cancer cells resist ferroptosis by recruiting FAM120A ...
Macrophage Ferroptosis Drives Lung Vessel Changes in GCN2 Deficiency
In a groundbreaking discovery poised to redefine our understanding of pulmonary vascular remodeling, a team of researchers have uncovered a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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