CRISPR cuts at wheat centromeres rewrite the karyotype in a single generation
Targeting CRISPR–Cas9 at centromeric retrotransposons in hexaploid bread wheat reconfigured up to 11 chromosomes in a single generation, yielding translocations, ...
Tag: karyotype
Stem Cell-Derived T Cells Offer New Human Model for Genotoxicity Testing
Researchers developed an in vitro micronucleus test using human induced pluripotent stem cell-derived T lymphocytes, which showed normal karyotype, intact ...
CRISPR centromere editing reshapes wheat chromosomes
A CRISPR–Cas9 strategy targeting centromeric repeats reconfigures up to 11 wheat chromosomes in one generation and yields heritable reciprocal translocations.
Maternal Balanced Translocation Behind Recurrent Fetal Holoprosencephaly in Case Report
A Chinese case report links nine consecutive failed pregnancies to a maternal balanced translocation between chromosomes 3 and 13, with ...
New assassin bug species from Myanmar reveals first fully inflated endosoma in reduviids
A newly described assassin bug from Myanmar's Dry Zone brings the first record of the genus Rhaphidosoma in Indochina, along ...
Chromosome fusions shaped frog evolution in Madagascar again and again
A comparative cytogenetic analysis of eight Malagasy mantelline frogs shows that chromosome number reduction from 2n = 26 to 2n ...
Hidden Chromosomal Diversity Uncovered in a Midge Once Thought Genetically Uniform
A survey of 19 natural populations reveals that the midge Chironomus agilis, long considered chromosomally uniform, harbors substantial inversion polymorphism, ...
GC-Rich Heterochromatin and Ribosomal Genes Mapped in Three Fungus-Farming Ants
A cytogenetic study of three Brazilian fungus-farming ant species reveals shared GC-rich heterochromatin and chromosome patterns that point to fissions ...
Gene Mutations Flag Poor Survival in Advanced Myeloproliferative Neoplasms
A retrospective review of 88 patients with advanced Philadelphia chromosome-negative myeloproliferative neoplasms identifies age, white blood cell count, prior myelofibrosis, ...
Tetraploid European paeonies ( Paeonia ) show a homogeneous karyotype asymmetry and structure
A cytogenetic study of four tetraploid European peony taxa reveals a homogeneous karyotype with no significant differences in chromosome asymmetry ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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