Copper-Driven Cell Death Offers a New Angle on Triple-Negative Breast Cancer
A new review outlines how the copper-dependent cell death regulator FDX1 may shape prognosis, metabolism, and treatment resistance in triple-negative ...
Tag: FDX1
FDX1 Loss Drives AML Resistance to Copper-Induced Cell Death
Research reveals that FDX1 downregulation in acute myeloid leukemia drives resistance to cuproptosis via the ROS/p53/ME1 axis, suggesting a new ...
Ceruloplasmin regulates cuproptosis-related changes in resistant prostate cancer cells
A preclinical study links ceruloplasmin and STPG3-AS1 to lipoylation and cuproptosis-associated changes in castration-resistant prostate cancer cells, but it does ...
METTL14 stabilizes FDX1 RNA and restrains clear cell kidney cancer
Preclinical experiments show that METTL14 stabilizes FDX1 RNA through m6A methylation, promoting cuproptosis and suppressing clear cell renal cell carcinoma ...
Copper Overload Triggers a Distinct Form of Cell Death That Could Transform Cancer Therapy
A new review details how excess copper induces cuproptosis, a mitochondria-dependent form of cell death that cancer cells are uniquely ...
Iron and Copper Cell Death Pathways May Hold Key to Beating Immunotherapy Resistance
A new review in Medical Oncology argues that simultaneously inducing the iron-driven cell death ferroptosis and the copper-driven cuproptosis, tuned ...
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver Cancer
A new review in Medical Oncology argues that simultaneously targeting copper-triggered cuproptosis and iron-dependent ferroptosis could open a powerful two-front ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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