Pancreatic Cancers With ATM Defects May Respond to Irinotecan, Study Finds
A new study combining real-world clinical data with CRISPR-edited cell models shows that pancreatic cancers with ATM or CHEK2 mutations ...
Tag: CRISPR
How Organoids Became Biology’s Most Powerful Miniature Laboratories
A new Nature Protocols tutorial by Munich researchers charts the full scope of organoid technology, from intestinal miniguts and brain ...
How Plants Rewind Their Cells: The Molecular Secrets of De Novo Organogenesis
A new review maps how hormones, gene networks, and epigenetic marks allow mature plant cells to revert to a pluripotent ...
Reprogramming Cells Inside the Body: The Regenerative Medicine Frontier Moving From Lab to Clinic
A new review in Advanced Science maps how in vivo direct reprogramming converts resident cells into functional replacements for damaged ...
Epigenetics Moves From Lab Bench to Bedside as Naples Conference Showcases Bold Advances
The 4th Clinical Epigenetics International Conference in Naples highlighted rapid progress in epigenetic mechanisms, editing technologies, and therapies for cancer, ...
Base Editors Correct Artemis Mutations, Offering New Hope for SCID Gene Therapy
Researchers have shown that CRISPR base editors can correct three pathogenic Artemis mutations ex vivo with up to 50 percent ...
Prime Assembly Enables Targeted Genomic Integration and Large-Scale DNA Rearrangements
A new prime editing-based strategy called prime assembly enables precise integration of large DNA fragments and programmable genomic rearrangements without ...
CRISPR Methylation Sensing Moves Toward Next-Generation Epigenetic Diagnostics
A new review details how CRISPR-Cas enzymes can be engineered to detect DNA and RNA methylation with single-nucleotide precision, charting ...
CRISPR gene editing could transform Africa’s staple crops, review finds
A new review finds CRISPR gene editing is rapidly advancing African staple crops but remains bottlenecked by infrastructure, regulation and ...
Common RT–qPCR Artifact May Inflate RNA Knockdown in CRISPR Experiments
New research shows that a pervasive RT–qPCR artifact can artificially inflate reported RNA knockdown by RNA-targeting CRISPR systems.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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