Choosing the Right Adenine Base Editor: New Study Maps the Rules for Precision Gene Editing
A systematic comparison of SpCas9-based adenine base editors in human cells reveals that conventional NGG-targeting editors deliver the highest activity ...
Tag: CRISPR
New Lipid Nanoparticles Supercharge CRISPR Delivery of Bulky Gene-Editing RNA
Researchers at the University of Toronto engineered an ionizable lipid, LC-1, that preserves its fusogenic structure when loaded with large ...
Soybean Gene GmISO5 Emerges as Master Switch for Health-Boosting Isoflavones and Virus Defense
A multi-omics study identifies the PEBP-family gene GmISO5 as a major regulator of soybean seed isoflavone biosynthesis and links its ...
Epigenetic Editing Steps Closer to the Clinic as Bioengineering Tools Mature
The EpiBio-24 conference in Amsterdam showcased maturing epigenetic engineering tools, durable gene silencing in animal models, and growing clinical momentum ...
Engineered mini CRISPR enzyme gets a 60-fold power boost for gene editing
Researchers transformed the inactive compact nuclease CgCas12n into a high-efficiency genome and base editor through arginine enrichment and guide RNA ...
CRISPR Beyond the Lab: Why Genome-Edited Plants Need a Sustainable Innovation System
A new Nature Plants commentary argues that the fate of CRISPR genome-edited crops depends less on molecular biology than on ...
Retracted Review Explored How Fish Genes Could Reshape Sustainable Aquaculture Feeds
A retracted Blue Biotechnology review traced how nutrigenomics, from RNA sequencing to CRISPR, could tailor fish diets to their genes ...
Bare Plant Cells Offer a Fast Lane to Better Carrots and a First for Bitter Gourd
Scientists have optimized protoplast isolation for carrot and achieved the first-ever protoplast isolation from bitter gourd, showing that carrot protoplasts ...
From Farm Waste to Factory Catalysts: The Rise of Sustainable Biocatalysis
A new review details how agricultural residues can feed sustainable biocatalysis while identifying the technical, economic, and policy barriers that ...
Sunflower Genes Could Hold the Key to Climate-Proof Crops in the World’s Driest Farmlands
A new review argues that sunflower's remarkable tolerance to combined drought, heat, salt, and pathogen stress makes it a powerful ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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