Tag: computational biology

Researchers used RFdiffusion, ProteinMPNN, and molecular dynamics to design novel protein binders against the human sweet taste receptor TAS1R2, creating ...

A new Frontiers in Bioinformatics editorial and seven accompanying studies reveal how different tools, workflows and training data can produce ...

Using an AI-driven computational pipeline, researchers have designed and prioritized five peptide candidates that target the glypican-3 protein found on ...

A new multiscale web server called InRegPep generates ensembles of amyloid protofilament models that matched experimental structures within 5 angstroms ...

A new two-step machine-learning framework called CLIMB and CLIFF computationally deconvolves bulk RNA-seq and drug sensitivity data into cell-type and ...

A new Frontiers in Aging collection argues that biological aging must be measured through combinations of epigenetic, proteomic and physiological ...

A new framework proposes translating natural-language prompts into machine-checkable constraints and a six-layer validator stack to make AI-driven genome design ...

Researchers introduced TAKO, a fast and interpretable method that ranks likely targets of a single-gene knockout using only wild-type single-cell ...

Researchers propose a closed-loop framework that unites AI-driven sequence design, molecular dynamics simulation, and experimental validation to rationally engineer high-affinity, ...

A new study of immunized mice shows that compartment size and clonal proliferation, rather than T cell receptor sequence features, ...