New Bispecific Antibody Redirects T Cells to Attack Melanoma Cells
Researchers at University Hospital Tübingen have engineered NG2-targeting bispecific antibodies that redirect T cells to kill melanoma cells, with a ...
Tag: cancer immunotherapy
Cancer Must Silence Its Own Viral Alarm to Become Malignant, Review Argues
A Nature Reviews Cancer review argues that escaping the antiviral viral mimicry response triggered by derepressed transposable elements is a ...
Viral HBX Protein Drives Immune Exhaustion in Liver Cancer Through MIF Signaling
A new study links the hepatitis B virus X protein to tumor-derived MIF signaling that drives CD8-positive T cell exhaustion ...
Armoured GPC3 CAR T Cells Show Promise Against Liver Cancer, but Hurdles Remain
An armoured GPC3-targeted CAR T cell therapy engineered to resist TGFβ-mediated immunosuppression showed promising initial results in 36 patients with ...
Where does the immune pressure go? New framework explains immunotherapy resistance
A new Molecular Cancer review proposes immune-pressure redistribution as a unifying framework explaining why patients resist PD-1/PD-L1 blockade and how ...
Light-Activated Cancer Therapy Shows Power to Trigger Body-Wide Immune Attack on Tumors
A systematic review of preclinical studies finds that photodynamic therapy can induce systemic antitumor immunity and abscopal effects, especially when ...
Receptor Occupancy Fails to Predict Immune Activation in Pembrolizumab Dosing Study
A translational modelling study finds that PD-1 receptor occupancy does not predict immune activation during pembrolizumab therapy, challenging current dosing ...
Exercise Could Help Cancer Patients on Immunotherapy, But Nobody Is Telling Them How
A qualitative study of patients with advanced bladder and kidney cancer on immune checkpoint inhibitor therapy finds they want structured ...
Subcutaneous Tarlatamab Shows Safety and Early Activity in Small Cell Lung Cancer
A phase 1b study presented at the IASLC 2026 World Conference on Lung Cancer found that subcutaneous tarlatamab was well ...
Lab Models Take Center Stage in the Race to Improve Cancer Immunotherapy
A systematic review of 75 studies maps how organoids, spheroids, tissue slices, and tumor-on-a-chip systems are being used to test ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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