Calreticulin-targeted L-asparaginase–flagellin conjugate boosts Salmonella’s antitumor effectiveness
Cancer researchers have reported a new strategy that combines bacterial tumor targeting, nutrient deprivation and immune stimulation in a single ...
Tag: cancer immunotherapy
Engineered macrophages reprogram tumor microenvironments, boosting antitumor immunity with IL-10–TLR9 switches
Cancer immunotherapy has transformed treatment for some patients, yet many solid tumors remain protected by a hostile biological environment that ...
PPARα Activation Overcomes Fibroinflammatory Anti-PD-1 Resistance in Liver Cancer via GSDME Pyroptosis
Hepatocellular carcinoma, the most common primary cancer of the liver, has become a major testing ground for immunotherapy. Drugs that ...
Membrane-Disrupting Peptide Triggers Immune-Stimulating Cancer Cell Death
Cancer researchers have designed a synthetic peptide that turns tumour cells into highly visible targets for the immune system by ...
Mitophagy-Driven Mitochondrial DNA Release Connects Radiation to Immunogenic Death in Pancreatic Cancer
Pancreatic cancer may be one of the most difficult cancers to treat, but new research points to a microscopic event ...
DNA Damage Response Pathways Inform New Cancer Immunotherapy Strategies
The DNA damage response (DDR) and the immune system may look like separate defense networks, but new research underscores how ...
KAIST Develops Antibodies With Cellular “Eyes” to Detect Cancer Mutations
KAIST researchers have reported a new class of T-cell-receptor-like antibodies designed to recognize an intracellular cancer mutation with high specificity. ...
Engineered Gut Bacteria Target Pancreatic Cancer in Promising Drug-Like Study
Pancreatic cancer is notoriously resistant to immunotherapy because many tumors develop an immune-suppressive, oxygen-poor “cold” microenvironment that blocks effective T ...
ZBP1 Links Genomic Stress to Tumor Immunity, New Study Finds
A new open-access Review in Ferroptosis and Oxidative Stress spotlights Z-nucleic acid-binding protein 1 (ZBP1), framing it as an emerging ...
Polyvinyl chloride boosts liver cancer radioresistance by blocking CD8⁺ T cells
In a groundbreaking study that could have significant implications for cancer treatment, researchers have uncovered a surprising link between polyvinyl ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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