Tag: cancer immunotherapy

New research shows that the TREX1 exonuclease suppresses anti-tumor immunity in mice by degrading short, MRE11-derived cytosolic DNA fragments that ...

A new review finds that pretreatment psychological distress is consistently associated with poorer outcomes after immune checkpoint inhibitor therapy, while ...

A narrative review argues that the acidic tumor microenvironment suppresses antitumor immunity and that targeting acidity is a preclinically supported ...

A Science Bulletin review outlines how multimodal artificial intelligence integrating molecular, cellular, and clinical data could refine immunotherapy decisions while ...

A recombinant overlapping peptide vaccine targeting HPV16 E7, combined with 4-1BB agonist antibody, eradicated established tumors in most treated mice ...

A new review maps how engineered DNA and RNA aptamers could enable targeted delivery and tumor microenvironment remodeling in precision ...

An NIH-funded phase 1/2 trial will test whether JAK inhibitors can protect pancreatic insulin-producing cells in people who develop diabetes ...

A mouse breast cancer study found that CD40-stimulated B cells recruited CD8+ T cells into tumors, influenced their organization and ...

A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially ...

A peer-reviewed study associated elevated circulating B cells before treatment with increased risk of immune checkpoint inhibitor–related colitis and found ...