Hidden Enzyme in B Cells Emerges as a Master Switch for Allergic Asthma
Deleting the Ssu72 phosphatase specifically in B cells sharply reduces IgE and IgG1 production and lung inflammation in a mouse ...
Tag: AMPK
Diabetes Drug Candidate AdipoRon Emerges as Unexpected Driver of Leukemia Blood Vessel Growth
A new correspondence in Molecular Biology Reports highlights evidence that the adiponectin receptor agonist AdipoRon promotes angiogenesis in B-cell leukemia ...
Copper and Iron Take Separate Roads to Keep Starving Cells Alive
New research in budding yeast reveals that copper and iron both extend the survival of nutrient-starved cells but do so ...
Turnip Extract Restores Blood Sugar Control in Diabetic Mice, Study Finds
A purified turnip root fraction rich in the flavones chrysin and apigenin improved glucose control, insulin sensitivity, and liver health ...
Immune Cell Enzyme p38 MAPK Emerges as a Molecular Fingerprint in Rare Nerve Diseases
A new study links elevated p38 MAPK activity in immune cells to multifocal motor neuropathy severity and shows that intravenous ...
One Drug, Three Species: Direct AMPK Activation Extends Lifespan Across Evolution
A direct activator of the conserved energy sensor AMPK extends lifespan in yeast, worms and flies, with genetic controls confirming ...
Starvation on a Petri Dish: How Fasting Rewires Cancer Cells and Exposes Their Weaknesses
A systematic review of eleven in vitro studies finds that fasting conditions consistently suppress IGF-1 and PI3K/AKT/mTOR signaling, inhibit glycolysis, ...
Cowhide Collagen Peptides Team Up With Bitter Melon to Fight High Blood Sugar
A new study finds that combining cowhide collagen peptides with bitter melon extract enhances blood-sugar-lowering effects in diabetic mice through ...
Protein Fragment From Thrombospondin-1 Emerges as Exercise-Powered Booster of Muscle and Metabolism
A study in Experimental & Molecular Medicine shows that the N-terminal fragment of thrombospondin-1 enhances muscle function and drives tissue-specific ...
Kinase Inhibitors Trigger Surprising Non-Catalytic Effects by Displacing Autoinhibitory Domains
A multimodal proteomics study shows that ATP-competitive kinase inhibitors displace autoinhibitory domains, driving unexpected non-catalytic functions relevant to drug development.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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