New Four-Axis Framework Maps the Hidden Diversity of Atypical Alzheimer’s Disease
A new review proposes a four-axis framework of clinical phenotype, biological context, network topography, and tempo to define the heterogeneity ...
Tag: Alzheimer’s disease
Alzheimer’s Disease Beyond Amyloid: What Atherosclerosis Teaches Us About Dementia Risk
A new perspective argues that Alzheimer's disease should be understood through the same multidimensional, risk-based lens that transformed atherosclerosis, with ...
Scientists Discover an RNA Molecule That Shields the Brain From Alzheimer’s Damage
New research shows that the long non-coding RNA Loc646329 protects neurons and improves memory in Alzheimer's model mice by sponging ...
Hidden Microproteins in the Human Brain Map a New Frontier of Alzheimer’s Disease
A new atlas catalogues 1,067 unannotated microproteins in the human frontal cortex and reveals that a subset, including an MKKS-derived ...
New Hydrophobic Tag Molecule Degrades DAPK1 and Cuts Tau Pathology in Alzheimer’s Mice
Scientists created CJ1, a hydrophobic tagging molecule that selectively destroys the DAPK1 kinase via the proteasome, reducing tau phosphorylation, neurofibrillary ...
New York Invests $500,000 in Binghamton Brain-on-a-Chip Dementia Research
Binghamton University has received a $500,000 SUNY Brain Institute grant to build advanced imaging and electrophysiology infrastructure for brain-on-a-chip dementia ...
Blood Test Algorithm Cuts Unnecessary Alzheimer’s PET Scans in Clinical Trial Screening
A USC-developed blood-based screening algorithm cut the rate of unnecessary PET scans among Alzheimer's clinical trial candidates from over 70 ...
New Single-Molecule Technique Reads Intact Tau Proteins at Unprecedented Scale
A new single-molecule technique called Iterative Mapping enables large-scale quantification of intact tau proteoforms in control samples, disease models, and ...
Chia Seeds Show Potent Enzyme-Blocking Power That Depends on Where They Grow
A new study links the enzyme-blocking, antidiabetic, and neuroprotective power of chia seeds to their geographical origin and phenolic chemistry.
Brain Protein ATIP Linked to Lower Amyloid Burden in Alzheimer’s Disease
Researchers have found that higher levels of the ATIP protein in postmortem brains of older adults with Alzheimer's disease are ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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