Tag: Alzheimer’s disease

A new study shows that silencing the protein PLSCR1 reduces inflammatory microglial activation and improves cognition in Alzheimer's model mice ...

A new review argues that somatic mosaicism is a pervasive feature of the human brain that links development, ageing and ...

A new computational study in Heliyon used pharmacophore modeling of marine-derived compounds to design synthetic gamma-secretase modulators that outperformed a ...

A narrative review of 119 studies finds that Alzheimer's disease biomarkers, including amyloid-beta, tau and neurofilament light chain, are consistently ...

An atlas of the aged human brain catalogs over 1,000 high-confidence microproteins, including an MKKS-encoded microprotein reduced in Alzheimer's disease ...

A new review in Biogerontology maps the complete molecular cascade by which the exercise hormone irisin travels from skeletal muscle ...

A new review proposes a four-axis framework of clinical phenotype, biological context, network topography, and tempo to define the heterogeneity ...

A new perspective argues that Alzheimer's disease should be understood through the same multidimensional, risk-based lens that transformed atherosclerosis, with ...

New research shows that the long non-coding RNA Loc646329 protects neurons and improves memory in Alzheimer's model mice by sponging ...

A new atlas catalogues 1,067 unannotated microproteins in the human frontal cortex and reveals that a subset, including an MKKS-derived ...