Tag: Alzheimer’s disease

A new review argues that shifting Alzheimer's disease genetic research from clinically diagnosed cohorts to neuropathologically confirmed ones is revealing ...

Researchers have developed an explainable multimodal machine-learning model that predicts with over 81 percent accuracy whether people with mild cognitive ...

A new review finds that induced pluripotent stem cells have transformed drug discovery for Alzheimer's disease, diabetes, arthritis and cancer ...

A new review argues that neurons can acquire senescence-like states in aging and neurodegenerative disease, but peripheral senescence markers cannot ...

A new study shows that silencing the protein PLSCR1 reduces inflammatory microglial activation and improves cognition in Alzheimer's model mice ...

A new review argues that somatic mosaicism is a pervasive feature of the human brain that links development, ageing and ...

A new computational study in Heliyon used pharmacophore modeling of marine-derived compounds to design synthetic gamma-secretase modulators that outperformed a ...

A narrative review of 119 studies finds that Alzheimer's disease biomarkers, including amyloid-beta, tau and neurofilament light chain, are consistently ...

An atlas of the aged human brain catalogs over 1,000 high-confidence microproteins, including an MKKS-encoded microprotein reduced in Alzheimer's disease ...

A new review in Biogerontology maps the complete molecular cascade by which the exercise hormone irisin travels from skeletal muscle ...