New Sequencing Methods Capture the Brain’s Hidden Vascular Cells
A newly published Nature Protocols paper details VINE-seq and MultiVINE-seq, streamlined workflows that isolate brain vessels and extract their nuclei ...
Tag: Alzheimer’s disease
Long-Lived Parents May Signal Slower Biological Ageing, Swedish Study Finds
A six-year Swedish cohort study finds that having long-lived parents predicts better cognition, less inflammation, healthier lipids and slower accumulation ...
APOE4 Splits Alzheimer’s Into Two Neurochemical Diseases, PET Imaging Study Reveals
A study of 387 amyloid-confirmed patients shows APOE4 carriers suffer cholinergic basal forebrain degeneration while non-carriers show dopaminergic loss, defining ...
Rigid Behaviours and Apathy Drive the Hidden Toll of Dementia Caregiving
A large transdiagnostic study shows that behavioural rigidity and apathy, not cognitive decline, are the strongest drivers of carer burden ...
Brain-Wide Activity Ties Subcortical Decline to Spreading Tau in Early Alzheimer’s
New research in Nature Communications shows that degeneration in deep subcortical brain regions becomes progressively linked to cortical tau accumulation ...
AI Brain Age Clock Trained on Death Risk Predicts Dementia Differently in Men and Women
A new study shows that an AI brain age model trained on mortality risk from MRI scans mediates how health ...
Lightweight AI Network Reads Brain Scans to Spot Alzheimer’s and Tumors With Striking Accuracy
Researchers have developed a compact four-block residual attention network that classifies Alzheimer's disease and brain tumors from MRI scans with ...
Alzheimer’s Biomarkers Lose Their Grip on Memory as Age Rises Past 80
A naturalistic study of 676 Stockholm memory clinic patients shows that the associations between amyloid-beta 42 and medial temporal atrophy ...
New AI Framework Weighs Evidence to Reveal When Medical Vision Models Truly Know
Researchers have developed UbiQVision, a framework that fuses explainable AI attributions from deep learning ensembles using Dempster–Shafer evidence theory to ...
Polyubiquitin Repositioning Reshapes Pathological Tau Fibril Structures in Dementia
Cryo-electron microscopy reveals that repositioned polyubiquitin chains outside the ordered core can remodel tau fibril ultrastructure and shift the protofilament ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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