Federated, explainable AI framework classifies Alzheimer’s disease from MRI and clinical data
A federated learning framework combining MRI and clinical data classifies Alzheimer's disease with reported accuracy up to 94.1 percent while...
Alzheimer’s Mouse Model Shows Early, Sex-Skewed Skeletal Muscle Decline
A mouse study finds that a triple transgenic Alzheimer's disease model develops measurable skeletal muscle mass, function and innervation deficits...
New Piperidine Acetamide Compounds Show Early Anti-Alzheimer’s Potential
Researchers in India synthesized five new piperidin-1-yl-phenyl-acetamide derivatives and found that the 2,5-dimethyl compound AS-5 showed the strongest acetylcholinesterase inhibition,...
Lab-Made Flavonoid Shields Nerve Cells From Oxidative Damage in Early Alzheimer’s Study
A laboratory-synthesised rare flavonoid, dichamanetin, protected retinoic acid-differentiated human neuroblastoma cells from hydrogen peroxide-induced damage in vitro, with the strongest...
Digital mobility metrics track Parkinson decline but offer no sample-size edge
A large observational study found that lower-back sensor measures of real-world walking declined over 24 months in Parkinson disease and...
Research report: Short-interval variability and test-retest reliability of Alzheimer’s disease plasma biomarkers in a clinically heterogenous cohort
A UCL study of 92 participants found core Alzheimer's plasma biomarkers showed high test-retest reliability over intervals from 30 minutes...
AI transformer detects REM sleep behavior disorder with 28-millisecond speed
A new multimodal transformer framework detects REM sleep behavior disorder with an AUC of 0.95 while running in 28 milliseconds,...
Exon-Skipping Splicing Changes Distinguish Alzheimer’s Disease from Progressive Supranuclear Palsy
A genomic study of temporal cortex tissue identifies hundreds of exon-skipping events that separate Alzheimer's disease from progressive supranuclear palsy,...
CSF APOE4 protein levels track tau pathology better than HDL measures in Alzheimer’s
A study of 144 ADNI participants found that CSF APOE4 protein levels, not HDL particle concentrations, were associated with tau...
Tau PET Imaging Shows Faster Tau Buildup Tracks Faster Decline in PSP
A longitudinal PET study using the QST-developed tracer florzolotau found that patients with progressive supranuclear palsy whose brain tau accumulated...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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