A meta-analysis of 29 randomised trials finds that drugs including melatonin and rotigotine significantly improve overall sleep quality in Parkinson's...

A new letter in the Journal of Clinical Sleep Medicine argues that REM sleep without atonia in people taking antidepressants...

Researchers have identified a morpholine-substituted chalcone, TC12, that inhibits monoamine oxidase B at 11 nanomolar with over 3,600-fold selectivity and...

New research shows that the microRNA miR-196a clears toxic mutant huntingtin aggregates in Huntington's disease by suppressing Rad23b, a ubiquitin...

A computational screening pipeline identified compound H34 as a promising dual inhibitor of acetylcholinesterase and monoacylglycerol lipase for Alzheimer's disease...

A new review links dysregulated polyamine metabolism to Alzheimer's, Parkinson's, ALS, and other neurological disorders, outlining molecular mechanisms and emerging...

Researchers have built a structured Italian adaptation of the CHAT and CLAN speech transcription system, reshaping standardized analysis of neurological...

A new tritium-labeled alpha-synuclein PET ligand, ³H-M503-1619, binds pathological aggregates in postmortem tissue from Lewy body diseases but not in...

A randomized controlled trial in npj Parkinson's Disease tested whether strategies for managing anxiety and the mental state can reduce...

A new study applying the revised Wilson and Cleary model finds that mental health and sexual function are as important...